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Genetic relatedness of the neuraminidase of influenza A strains Nav2, Nav3, and Nav6

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Summary

By molecular hybridization and by neuraminidase inhibition tests it is shown that all influenza A strains tested carrying an Nav3 or Nav2 neuraminidase (NA) are genetically highly related in their NA genes and cross-react serologically with specific antineuraminidase sera. The Nav6 strains exhibit a very low RNase protection after hybridization and do not cross-react serologically with Nav2 or Nav3 strains. Thus, the Nav2 and Nav3 strains comprise one group which is distinct from that of Nav6 strains.

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Authors and Affiliations

  1. Institut für Virologie, Justus Liebig-Universität Giessen, Giessen, Germany

    C. Scholtissek & R. Rott

  2. The Invanovsky Institute of Virology, Moscow, USSR

    D. K. Lvov & I. A. Myasnikova

Authors
  1. C. Scholtissek
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  2. R. Rott
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  3. D. K. Lvov
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  4. I. A. Myasnikova
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Scholtissek, C., Rott, R., Lvov, D.K. et al. Genetic relatedness of the neuraminidase of influenza A strains Nav2, Nav3, and Nav6. Archives of Virology 65, 325–328 (1980). https://doi.org/10.1007/BF01314548

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  • DOI: https://doi.org/10.1007/BF01314548

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