Skip to main content
Log in

Complementation with an avian influenza virus is required for synthesis of M protein of a human strain in chicken erythrocytes

  • Brief Report
  • Published:
Archives of Virology Aims and scope Submit manuscript

Summary

The M protein of avian, but not human, strains of influenza A viruses is synthesized in infected chicken erythrocytes. In dual infections an avian strain complemented the human virus and both the human and avian M proteins were expressed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Attardi, G., Parnas, H., Hwang, M.-I. H., Attardi, B.: Giant-size, rapidly labelled nuclear ribonucleic acid and cytoplasmic messenger ribonucleic acid in immature duck erythrocytes. J. mol. Biol.20, 145–182 (1966).

    Google Scholar 

  2. Blanchet, J. P.: Chicken erythrocyte membranes: Comparison of nuclear and plasma membrane from adults and embryos. Exp. Cell Res.84, 159–166 (1974).

    Google Scholar 

  3. Bosch, F. X., Hay, A. J., Skehel, J. J.: RNA and protein synthesis in a permissive and an abortive influenza infection. In:Mahy, B. W. J., Barry, R. D. (eds.), Negative Strand Viruses and the Host Cell, 465–474. London: Academic Press 1978.

    Google Scholar 

  4. Cook, R. F., Avery, R. J., Dimmock, N. J.: Infection of chicken erythrocytes with influenza and other viruses. Infect. Immun.25, 396–402 (1979).

    Google Scholar 

  5. Dimmock, N. J., Carver, A. S., Kennedy, S. I. T., Lee, M. R., Luscombe, S.: Internal proteins of influenza virus:35S-methionine peptide maps as genetic markers. J. gen. Virol.36, 503–513 (1977).

    Google Scholar 

  6. Fawcett, D. W., Witebsky, F.: Observations on the ultrastructure of nucleated erythrocytes and thrombocytes with particular reference to the structural basis of their discoidal shap. Z. Zellforsch.62, 785–806 (1964).

    Google Scholar 

  7. Kruger, C., Seifart, K. H.: RNA polymerase differentiation of avian erythrocytes. Exp. Cell Res.106, 446–450 (1977).

    Google Scholar 

  8. Lohmeyer, J., Talens, L. T., Klenk, H. D.: Bio-synthesis of the influenza virus envelope in abortive infection. J. gen. Virol.42, 73–78 (1979).

    Google Scholar 

  9. Longacre, S. S., Rutter, W. J.: Nucleotide polymerase in the developing avian erythrocytes. J. biol. Chem.252, 273–283 (1977).

    Google Scholar 

  10. Lucas, A. M., Jamroz, C.: Atlas of avian haematology. U.S. Department of Agriculture. Monograph No. 25 (1961).

  11. MacLean, N., Madgwick, W. J.: The RNA of chicken erythrocytes. Cell Differ.2, 271–278 (1973).

    Google Scholar 

  12. Mahy, B. W. J., Carroll, A. R., Brownson, J. T., McGeoch, D. J.: Block to influenza virus replication in cells pre-irradiated with ultraviolet light. Virology83, 150–162 (1977).

    Google Scholar 

  13. Minor, P. D., Dimmock, N. J.: Inhibition of synthesis of influenza virus proteins: Evidence for two host cell-dependent events during multiplication. Virology67, 114–123 (1975).

    Google Scholar 

  14. Minor, P. D., Dimmock, N. J.: Selective inhibition of influenza virus protein synthesis by inhibitors of DNA function. Virology78, 393–406 (1977).

    Google Scholar 

  15. Minor, P. D., Hart, J. G., Dimmock, N. J.: Influence of the host cell on proteins synthesized by different strains of influenza virus. Virology97, 482–487 (1979).

    Google Scholar 

  16. Romanoff, A. L.: The avian embryo. New York: The Macmillan Co. 1960.

    Google Scholar 

  17. Scherrer, K., Marcaud, L., Zajdela, F., London, F. M., Gros, F.: Patterns of RNA metabolism in a differentiated cell: A rapidly labelled unstable 60S RNA with messenger properties in duck erythroblasts. Proc. Nat. Acad. Sci. U.S.A.56, 1571–1578 (1966).

    Google Scholar 

  18. Schjeide, O. A., McCandless, R. G., Munn, R. J.: Relationships between haematic synthesis and morphological structures in adult and fetal red cells. Growth28, 29–39 (1964).

    Google Scholar 

  19. Valcavi, P., Conti, G., Schito, G. C.: Macromolecular syntheses during abortive infection of KB cells by influenza virus. In:Mahy, B. W. J., Barry, R. D. (eds.), Negative Strand Viruses and the Host Cell, 475–481. London: Academic Press 1978.

    Google Scholar 

  20. Williams, A. F.: DNA synthesis in purified populations of erythroid cells. J. Cell Sci.10, 27–46 (1972).

    Google Scholar 

  21. Zentgraf, H., Deumling, B., Jarasch, E. D., Franke, W. W.: Nuclear membrane and plasma membrane from hen erythrocytes. J. biol. Chem.246, 2986–2995 (1971).

    Google Scholar 

  22. Zentgraf, H., Scheer, V., Franke, W. W.: Characterization and localization of the RNA synthesized in mature avian erythrocytes. Exp. Cell Res.96, 81–95 (1975).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

With 4 Figures

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cook, R.F., Avery, R.J. & Dimmock, N.J. Complementation with an avian influenza virus is required for synthesis of M protein of a human strain in chicken erythrocytes. Archives of Virology 65, 319–324 (1980). https://doi.org/10.1007/BF01314547

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01314547

Keywords

Navigation