Summary
Purified HBsag has a complex structure comprising 8 polypeptides. Some of these polypeptides are immunogenic and induce both humoral and cell-mediated immunity in guinea pigs.
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Mineva, E., Teoharova, M., Ditzov, S. et al. Polypeptide composition of HBsag. Archives of Virology 55, 87–91 (1977). https://doi.org/10.1007/BF01314482
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DOI: https://doi.org/10.1007/BF01314482