Skip to main content
SpringerLink
Log in

Effects of various proteases on the glycoprotein composition and the infectivity of influenza C virus

  • Brief Report
  • Published:
Archives of Virology Aims and scope Submit manuscript

Summary

Trypsin and elastase activated the infectivity of influenza C virus by cleaving a precursor glycoprotein gp88 into subunits gp65 and gp30, whereas chymotrypsin and thermolysin did not.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Cleveland, R. W., Fischer, S. G., Kirscher, M. W., Laemmli, U. K.: Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. J. biol. Chem.252, 1102–1106 (1977).

    Google Scholar 

  2. Compans, R. W., Bishop, D. H., Meier-Ewert, H.: Structural components of influenza C virions. J. Virol.21, 658–665 (1977).

    Google Scholar 

  3. Compans, R. W., Klenk, H.-D., Caliguili, L. A., Choppin, P. W.: Influenza virus proteins. I. Analysis of polypeptides of the virion and identification of spike glycoproteins. Virology42, 880–889 (1970).

    Google Scholar 

  4. Glossmann, H., Neville, D. M., Jr.: Glycoproteins of cell surfaces. A comparative study of three different cell surfaces of the rat. J. biol. Chem.246, 6339–6346 (1971).

    Google Scholar 

  5. Herrler, G., Compans, R. W., Meier-Ewert, H.: A precursor glycoprotein in influenza C virus. Virology99, 49–56 (1979).

    Google Scholar 

  6. Kashiwazaki, H., Homma, M., Ishida, N.: Assay of Sendai virus by immunofluorescence and hemadsorbed cell-counting procedures. Proc. Soc. exp. Biol. Med.120, 134–138 (1965).

    Google Scholar 

  7. Kendal, A. P.: A comparison of “influenza C” with prototype myxoviruses. Receptor-destroying activity (neuraminidase) and structural polypeptides. Virology65, 87–99 (1975).

    Google Scholar 

  8. Klenk, H.-D., Rott, R., Orlich, M.: Further studies on the activation of influenza virus by proteolytic cleavage of haemagglutinin. J. gen. Virol.36, 151–161 (1977).

    Google Scholar 

  9. Laemmli, U. K.: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London)227, 680–685 (1970).

    Google Scholar 

  10. Landsberger, F. R., Lenard, J., Paxton, J., Compans, R. W.: Spin lable ESR study of the lipid-containing membrane of influenza virus. Proc. Natl. Acad. Sci. U.S.A.68, 2579–2583 (1971).

    Google Scholar 

  11. Lazarowitz, S. G., Choppin, P. W.: Enhancement of the infectivity of influenza A and B viruses by proteolytic cleavage of the hemagglutinin polypeptide. Virology68, 440–454 (1975).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Bacteriology, Yamagata University School of Medicine, Yamagata Zao-Iida, Japan

    K. Sugawara, M. Ohuchi, K. Nakamura & M. Homma

Authors
  1. K. Sugawara
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Ohuchi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. Nakamura
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M. Homma
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

With 2 Figures

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sugawara, K., Ohuchi, M., Nakamura, K. et al. Effects of various proteases on the glycoprotein composition and the infectivity of influenza C virus. Archives of Virology 68, 147–151 (1981). https://doi.org/10.1007/BF01314445

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01314445

Keywords

Search

Navigation