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Detection of antibodies to strain-specific and cross-reactive antigenic determinants on the haemagglutinin of influenza viruses A/Texas/1/77 and A/Bangkok/1/79 in human sera

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Summary

The antibody response to antigenic determinants on the haemagglutinin molecule of A/Texas/77 and A/Bangkok/79 strains was analysed by SRH of virus-absorbed sera, in human sera collected from persons of different ages following natural infection or immunization. The results have shown, as expected, low and high frequencies of strain-specific antibodies in sera of adults and young children respectively. However, in the latter group antibodies to cross-reactive antigens were also detected.

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Authors and Affiliations

  1. Department of Virology, Istituto Superiore di Sanità, I-00161, Rome, Italy

    G. Mancini, I. Donatelli, G. Arangio Ruiz & C. Rozera

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  1. G. Mancini
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  2. I. Donatelli
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  3. G. Arangio Ruiz
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  4. C. Rozera
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Mancini, G., Donatelli, I., Arangio Ruiz, G. et al. Detection of antibodies to strain-specific and cross-reactive antigenic determinants on the haemagglutinin of influenza viruses A/Texas/1/77 and A/Bangkok/1/79 in human sera. Archives of Virology 79, 117–121 (1984). https://doi.org/10.1007/BF01314309

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  • DOI: https://doi.org/10.1007/BF01314309

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