Skip to main content
Log in

Analysis of antigenic differences between sixteen phocine distemper virus isolates and other morbilliviruses

  • Brief Report
  • Published:
Archives of Virology Aims and scope Submit manuscript

Summary

Monoclonal antibodies against a phocine morbillivirus isolate (PDV 2558/Han 88) were able to discriminate sixteen PDV isolates from any other morbillivirus species providing further evidence that PDV should be regarded a new species in the morbillivirus genus.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Barrett T, Belsham GJ, Subbarao SM, Evans SA (1989) Immunization with a vaccinia recombinant expressing the F protein protects rabbits from challenge with a lethal dose of rinderpest virus. Virology 170:11–18

    Google Scholar 

  2. Barrett T, Crowther J, Osterhaus ADME, Subbarao SM, Groen J, Haas L, Mamaev LV, Titenko AM, Grachev MA, Visser IKG, Bostock CJ (1991) Molecular, biological and serological studies on the recent seal virus epizootic in Europe and Siberia. Sci Total Environ (in press)

  3. Bengtson JL, Boveng P, Franzen U, Have P, Heide-Jörgensen MP, Härkönen TJ (1990) Antibodies to canine distemper in Antarctic seals. Marine Mammal Sci (in press)

  4. Blixenkrone-Möller M, Svansson V, Örvell C, Have P (1990) Phocine distemper virus — a threat to terrestrial mammals? Vet Rec 127: 263–264

    Google Scholar 

  5. Bostock CJ, Barrett T, Crowther JR (1990) Characterization of the European seal morbillivirus. Vet Microbiol 23: 351–360

    Google Scholar 

  6. Cosby SL, McQuaid S, Duffy N, Lyons C, Rima BK, Allan GM, McCullough SJ, Kennedy S, Smyth JA, McNeilly F, Craig C, Örvell C (1988) Characterization of seal morbillivirus. Nature 336: 115–116

    Google Scholar 

  7. Curran MD, O'Loan D, Rima BK, Kennedy S (1990) Nucleotide sequence analysis of phocine distemper virus reveals distinctness from canine distemper virus. Vet Rec 127: 430–431

    Google Scholar 

  8. Dietz R, Ansen CT, Have P, Heide-Jörgensen MP (1989) Clue to seal epizootic? Nature 338: 627

    Google Scholar 

  9. Domingo M, Ferre L, Pumaorola M, Marco A, Plana J, Kennedy S, McAliskey M, Rima BK (1990) Morbillivirus in dolphins. Nature 348: 21

    Google Scholar 

  10. Grachev MA, Kumarev VP, Mamev LV, Zorin VL, Baranova LV, Denikina NN, Belikov SI, Petrov EA, Kolesnik VS, Kolesnik RS, Dorofeev VM, Beim AM, Kudelin VN, Nagievea FG, Sidorov VN (1989) Distemper virus in Baikal seals. Nature 338: 209

    Google Scholar 

  11. Greiser-Wilke I, Moennig V, Coulibaly COZ, Dahle J, Leder L, Liess B (1990) Identificaton of conserved epitopes on a hog cholera protein. Arch Virol 111: 213–225

    Google Scholar 

  12. Haas L, Subbarao SM, Harder TC, Liess B, Barret T (1991) Detection of phocid distemper virus RNA in seal tissues by using slot hybridisation and polymerase chain amplification assay: genetic evidence that the virus is different from canine distemper virus. J Gen Virol (in press)

  13. Hall WW, Lamb RA, Choppin PW (1980) The polypeptides of canine distemper virus: synthesis in infected cells and relatedness to the polypeptides of other morbilliviruses. Virology 100: 433–449

    Google Scholar 

  14. Harder TC (1990) Morbillivirusinfektionen bei Pinnipeda: Untersuchungen zur Charakterisierung, Antigenverwandtschaft und Pathogenität von Morbilliviren phociner Herkunft. Thesis, Hannover Veterinary School, Hannover, Federal Republic of Germany

    Google Scholar 

  15. Harder TC, Willhaus T, Frey HR, Liess B (1990) Morbillivirus infection of seals (Phoca vitulina) during the 1988 epizootic in the bay of Heligoland. III. Transmission studies of cell culture-propagated phocine distemper virus in harbour seals (Phoca vitulina) and a grey seal (Halichoerus grypus): clinical, virological and serological results. J Vet Med B 37: 641–650

    Google Scholar 

  16. Jäger M, Liess B, Harder TC, Ising S, Stoye M (1990) Experimental inoculation of beagle dogs permits serological differentiation of phocine and canine distemper virus. Wien Tierärztl Monatsschr 77: 105–108

    Google Scholar 

  17. Kennedy S, Smyth JA, McCullough J, Allan GM, McNeilly F, McQuaid S (1988) Confirmation of cause of recent seal deaths. Nature 335: 404

    Google Scholar 

  18. Kennedy S, Smyth JA, Cush PF, McCullough SJ, Allan GM, McQuaid S (1988) Viral distemper now found in porpoises. Nature 336: 21

    Google Scholar 

  19. Kohama T, Sato TA, Kobune F, Sugiura A (1985) Maturation of measles virus hemagglutinin glycoprotein. Arch Virol 85: 257–268

    Google Scholar 

  20. Laemmli UK (1970) Cleavage of the structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680–685

    Google Scholar 

  21. Liess B, Frey HR, Zagahawa A (1989) Morbillivirus in seals: isolation and some growth characteristics in cell culture. Dtsch Tierärztl Wochenschr 96: 180–182

    Google Scholar 

  22. Liess B, Frey HR, Zagahawa A, Stede M (1989) Morbillivirus infections of seals (Phoca vitulina) during the 1988 epidemic in the bay of Heligoland. I. Mode, frequency and significance of cultural virus isolation and neutralizing antibody detection. J Vet Med B 36: 601–608

    Google Scholar 

  23. Lyons C, Henderson G, Duffy N, Rima BK, Ronald K, Trudgett A (1990) Studies on the antigens of phocine distemper virus. In: Abstracts 8th Int Congr Virol, Berlin 1990, 230

  24. Mahy BW, Barrett T, Evans S, Anderson EC, Bostock CJ (1988) Characterization of a seal morbillivirus. Nature 336: 115

    Google Scholar 

  25. Malvoisin E, Wild TF (1990) Contribution of measles virus fusion protein in protective immunity: anti-F monoclonal antibodies neutralize virus infectivity and protect mice against challenge. J Virol 64: 5160–5162

    Google Scholar 

  26. Örvell C, Blixenkrone-Möller M, Svansson V, Have P (1990) Immunological relationships between phocid and canine distemper virus studied with monoclonal antibodies. J Gen Virol 71: 2085–2092

    Google Scholar 

  27. Osterhaus ADME, Vedder E (1988) Identification of virus causing recent seal deaths. Nature 335: 20

    Google Scholar 

  28. Osterhaus ADME, Groen J, De Vries P, Uytdehaag FGCM, Klingeborn B, Zarnke R (1988) Canine distemper virus in seals. Nature 335: 403–404

    Google Scholar 

  29. Osterhaus ADME, Groen J, Uytdehaag FGCM, Visser IGK, Vedder E, Crowther J, Bostock CJ (1989) Morbillivirus infections in European seals before 1988. Vet Rec 125: 326

    Google Scholar 

  30. Rima BK (1983) The proteins of morbilliviruses. J Gen Virol 64: 1205–1219

    Google Scholar 

  31. Rima BK, Cosby SL, Duffy N, Lyons C, O'Loan D, Kennedy S, McCullough SJ, Smyth JA, McNeilly F (1990) Humoral immune response of seals infected by phocine distemper virus. Res Vet Sci 49: 114–116

    Google Scholar 

  32. Sato TA, Hayami M, Yamanouchi K (1981) Analysis of structural proteins of measles, canine distemper, and rinderpest virus. Jap J Med Sci Biol 34: 355–364

    Google Scholar 

  33. Shesberadaran H, Norrby E, McCullough KC, Carpenter WC, Örvell C (1986) The antigenic relationship between measles, canine distemper and rinderpest virus studied with monoclonal antibodies. J Gen Virol 67: 1381–1392

    Google Scholar 

  34. Stephenson JR, Ter Meulen V (1979) Antigenic relationships between measles and canine distemper viruses: comparison of immune response in animals and humans to individual virus-specific polypeptides. Proc Natl Acad Sci USA 76: 6601–6605

    Google Scholar 

  35. Taggart RT, Samloff M (1983) Stable antibody-producing murine hybridomas. Science 219: 1228–1230

    Google Scholar 

  36. Varsanyi TM, Jörnvall H, Norrby E (1985) Isolation and characterization of the measles virus F1-polypeptide: comparison with other paramyxovirus fusion proteins. Virology 147: 110–117

    Google Scholar 

  37. Visser IGK, Kumarev VP, Örvell C, De Vries P, Broeders HWJ, van de Bildt MWG, Groen J, Teppema JS, Burger MC, UytdeHaag FGCM, Osterhaus ADME (1990) Comparison of two morbilliviruses isolated from seals during outbreaks of distemper in North West Europe and Siberia. Arch Virol 111: 149–164

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Harder, T.C., Moennig, V., Greiser-Wilke, I. et al. Analysis of antigenic differences between sixteen phocine distemper virus isolates and other morbilliviruses. Archives of Virology 118, 261–268 (1991). https://doi.org/10.1007/BF01314036

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01314036

Keywords

Navigation