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Tumour induction by transplacental infection with polyoma virus of the F1 generation of wistar rats

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Summary

Intravenous polyoma virus inoculation into pregnant Wistar rats resulted in transplacental infection of the foetus, causing tumours and hydronephroses. Cyclosporin A reduced these effects significantly.

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Authors and Affiliations

  1. Medical School of Hannover, Institute of Virology, Hannover, Federal Republic of Germany

    W. Verhagen, C. M. Hubert & E. Mohtaschem

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  1. W. Verhagen
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  2. C. M. Hubert
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  3. E. Mohtaschem
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Verhagen, W., Hubert, C.M. & Mohtaschem, E. Tumour induction by transplacental infection with polyoma virus of the F1 generation of wistar rats. Archives of Virology 133, 459–465 (1993). https://doi.org/10.1007/BF01313783

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  • DOI: https://doi.org/10.1007/BF01313783

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