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Incomplete replication of human parainfluenza virus type 2 in mouse L929 cells

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Summary

Human parainfluenza virus type 2 (HPIV-2) was tested for its ability to replicate in murine L929 cells. L929 cells were non-permissive for replication of HPIV-2. Interferon produced endogenously played no role in its incomplete replication. The mechanism by which growth of HPIV-2 was suppressed in L929 cells was studied. Synthesis of virus-specific polypeptides, particularly glycoprotein(s), was suppressed in HPIV-2-infected L929 cells. The HN mRNA could scarcely be detected in virus-infected L929 cells.

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References

  1. Cervera M, Dreyfuss G, Penman S (1981) Messenger RNA is translated when associated with the cytoskeletal framework in normal and VSV-infected HeLa cells. Cell 23. 113–120

    Google Scholar 

  2. Ito Y, Tsurudome M, Hishiyama M (1985) Mumps virus persistence in mouse L 929 cells. Microbiol Immunol 29: 847–857

    Google Scholar 

  3. Homma M (1971) Trypsin action on the growth of Sendai virus in tissue culture cells. I. Restoration of the infectivity for L cells by direct action of trypsin on L cell-borne Sendai virus. J Virol 8: 619–629

    Google Scholar 

  4. Homma M, Ohuchi M (1973) Trypsin action on the growth of Sendai virus in tissue culture cells. III. Structural differences of Sendai viruses grown in eggs and tissue culture cells. J Virol 12: 1457–1465

    Google Scholar 

  5. Nagai Y, Ito Y, Hamaguchi M, Yoshida T, Matumoto T (1981) Relation of interferon production to the limited replication of Newcastle disease virus in L cells. J GenVirol 55: 109–116

    Google Scholar 

  6. Hamaguchi M, Nishikawa K, Toyoda T, Yoshida T, Hanaichi T, Nagai Y (1985) Transcriptive complex of Newcastle disease virus. II. Structural and functional assembly associated with the cytoskeletal framework. Virology 147: 295–308

    Google Scholar 

  7. Tsurudome M, Nishio M, Komada H, Bando H, Ito Y (1989) Extensive antigenic diversity among human parainfluenza type 2 virus isolates and immunological relationships among paramyxoviruses revealed by monoclonal antibodies. Virology 171: 38–48

    Google Scholar 

  8. Yamada A, Tsurudome M, Hishiyama M, Ito Y (1984) Abortive infection of mumps virus in murine cell lines. J Gen Virol 65: 973–980

    Google Scholar 

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Authors and Affiliations

  1. Department of Microbiology, Mie University School of Medicine, Edobashi, Mie-Prefecture, Japan

    Yasuhiko Ito, Masato Tsurudome, Hisanori Bando, Hiroshi Komada & Machiko Nishio

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  1. Yasuhiko Ito
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  2. Masato Tsurudome
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  3. Hisanori Bando
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  4. Hiroshi Komada
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  5. Machiko Nishio
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Ito, Y., Tsurudome, M., Bando, H. et al. Incomplete replication of human parainfluenza virus type 2 in mouse L929 cells. Archives of Virology 108, 137–144 (1989). https://doi.org/10.1007/BF01313751

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  • DOI: https://doi.org/10.1007/BF01313751

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