Skip to main content

Recurrent obstructive jaundice caused by fibrolamellar hepatocellular carcinoma

Summary

A 24-year-old man with hepatocellular carcinoma presented with recurrent obstructive jaundice caused by bile duct invasion and distal migration of necrotic tumor fragments. After resection of an isolated left lobe tumor, he was well for 2 years until he again presented with obstructive jaundice caused by necrotic tumor and clot in the common bile duct. Analysis of his tumor revealed the fibrolamellar histologic variant of hepatocellular carcinoma. This case is unique in that the hepatocellular carcinoma was of the fibrolamellar variant and presented both intially and when recurrent 2 years later with obstructive jaundice caused by invasion of the common bile duct.

This is a preview of subscription content, access via your institution.

References

  1. Ihde DC, Sherlock P, Winawer SJ, Fortner JG: Clinical manifestations of hepatoma. A review of 6 years' experience at a cancer hospital. Am J Med 56:83–91, 1974

    Google Scholar 

  2. Kew MC. Tumors of the liver.In Hepatology. A texbook of Liver Disease. D Zakim, TD Boyer (eds) Philadelphia, WB Saunders, 1982, pp 1048–1084

    Google Scholar 

  3. Afroudakis A, Bhuta SM, Ranganath KA, Kaplowitz N: Obstructive jaundice caused by hepatocellular carcinoma. Report of three cases. Am J Dig Dis 23:609–617, 1978

    Google Scholar 

  4. vanSonnenberg E, Ferrucci JT Jr: Bile duct obstruction in hepatocellular carcinoma (hepatoma)-clinical and cholangiographic characteristics. Radiology 130:7–13, 1979

    Google Scholar 

  5. Kojiro M, Kawabata K, Kawano Y, Shirai F, Takemoto N Nakashima T: Hepatocellular carcinoma presenting as intrabile duct tumor growth. A clinicopathologic study of 24 cases. Cancer 49:2144–2147, 1982

    Google Scholar 

  6. Craig JR, Peters RL, Edmondson HA, Omata M: Fibrolamellar carcinoma of the liver: A tumor of adolescents and young adults with distinctive clinico-pathologic features. Cancer 46:372–379, 1980

    Google Scholar 

  7. Berman MM, Libbey NP, Foster JH: Hepatocellular carcinoma. Polygonal cell type with fibrous stroma-an atypical variant with a favorable prognosis. Cancer 46:1448–1455, 1980

    Google Scholar 

  8. Slavutin LJ, Diamond N: Case report. Hepatocellular carcinoma with lamellar fibrosis: An important histological variant. Pathology 13:775–781, 1980

    Google Scholar 

  9. Wong LK, Link DP, Frey CF, Ruebner BH, Tesluk H, Pimstone NR: Fibrolamellar hepatocarcinoma: radiology, management, and pathology. Am J Radiol 139:172–175, 1982

    Google Scholar 

  10. Chuong JJH, Livstone EM, Barwick KW: The histopathologicc and clinical indicators of prognosis in hepatoma. J Clin Gastroenterol 4:547–552, 1982

    Google Scholar 

  11. Lack EE, Neave C, Vawter GF: Hepatocellular carcinoma. Review of 32 cases in childhood and adolescence. Cancer 52:1510–1515, 1983

    Google Scholar 

  12. Farhi DC, Shikes RH, Murari PJ, Silverberg SG: Hepatocellular carcinoma in young people. Cancer 52:1516–1525, 1983

    Google Scholar 

  13. Edmondson HA, Peters RL: Neoplasms of the liver.In Diseases of the Liver, 5th eded. L. Schiff, ER Schiff (eds.) Philadelphia JB Lippincott, 1982, pp 1101–1157

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Albaugh, J.S., Keeffe, E.B. & Krippaehne, W.W. Recurrent obstructive jaundice caused by fibrolamellar hepatocellular carcinoma. Digest Dis Sci 29, 762–767 (1984). https://doi.org/10.1007/BF01312952

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01312952

Keywords

  • Public Health
  • Carcinoma
  • Migration
  • Bile Duct
  • Hepatocellular Carcinoma