Skip to main content
SpringerLink
Log in

Effect of diet on intestinal xylose absorption in dogs

  • Original Articles
  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

Abstract

The absorption of xylose at different levels of the intestine was compared in five dogs receiving diets containing either wheat bran, polyethylene particles (PE), or horse-bean hulls. The absorption was determined by serial collection of the interstitial fluid (ISF) in different parts of the small intestine and colon, and blood concentration after the administration ofd-xylose as a solution (0.5 g/kg body weight) into the duodenal bulb. Xylose was mostly absorbed from the duodenum, and its concentration in the duodenal ISF and in plasma was reduced on a diet containing fiber, irrespective of the nature of fiber. In contrast, a negative linear relation between the mean retention time of digesta in the small intestine and the amount of xylose absorbed by duodenum was evidenced (r=−0.843). The results indicate that changes in transit linked to the presence of fiber in a diet are a major operative factor in the rate of carbohydrate absorption. They suggest that the absorption can be affected by a relatively minor change in the intestinal transit of digesta.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Morgan LM, Goulder TJ, Tsiolakis D, Marks V, Alberti KGMM: The effect of unabsorbable carbohydrate on gut hormones: Modification of postprandial GIP secretion by guar, Diabetologia 17:85–99, 1979

    Google Scholar 

  2. Findlay JM, Smith AN, Mitchell WD, Anderson AJB, Eastwood MA: Effects of unprocessed bran on colon function in normal subjects and in diverticular disease. Lancet 1:146, 1974

    Google Scholar 

  3. Bardon T, Fioramonti J: Nature of the effect of bran on digestive transit time in pig. Br J Nutr 50:685–690, 1983

    Google Scholar 

  4. Ruckebusch Y, Buéno L, Fioramonti J: Constituants alimentaires et motricité digestive. Reprod Nutr Dev 21:749–771, 1981

    Google Scholar 

  5. Buéno L, Praddaude F, Fioramonti J, Ruckebusch Y: Effect of dietary fiber on gastrointestinal motility and jejunal transit time in dogs. Gastroenterology 80:701–707, 1981

    Google Scholar 

  6. Kiehm TG, Anderson JW, Ward K: Beneficial effects of a high-carbohydrate, high-fiber diet on hyperglycemia diabetic men. Am J Clin Nutr 29:895–899, 1976

    Google Scholar 

  7. Jenkins DJA, Goff DV, Leeds AR, Gassul AR, Wolever TMS, Goff DV, Alberti KGMM, Hockaday TDR: Unabsorbable carbohydrates and diabetes: decreased postprandial hyperglycemia. Lancet 2:172–174, 1976

    Google Scholar 

  8. Miranda PM, Horwitz DL: High-fiber diets in the treatment of diabetes mellitus. Ann Intern Med 88:482–486, 1978

    Google Scholar 

  9. Gordon DT, Besch-Williford C, Ellersieck MR: The action of cellulose on the intestinal mucosa and element absorption by the rat, J Nutr 113:2545–2556, 1983

    Google Scholar 

  10. Jacobs LR, Lupton JR: Effect of dietary fibers on rat large bowel mucosal growth and cell proliferation. Am J Physiol 246:G378-G385, 1984

    Google Scholar 

  11. Schwartz SE, Levine GD: Effects of dietary fiber on intestinal glucose absorption and glucose tolerance in rats. Gastroenterology 79:833–836, 1980

    Google Scholar 

  12. Jenkins DJA, Wolever TMS, Leeds AR, Gassull MA, Haisman P, Dilawari J, Goff DV, Metz GL, Alberti KGMM: Dietary fibres, fibre analogues and glucose tolerance: Importance of viscosity. Br Med J 1:1392–1394, 1978

    Google Scholar 

  13. Cherbut C, Ruckebusch Y: The effect of indigestible particles on digestive transit and colonic motility in dogs and pigs. Br J Nutr 53:549–557, 1985

    Google Scholar 

  14. Elsenhans B, Zenker D, Caspary WF: Guaran effect on rat intestinal absorption. Gastroenterology 86:645–653, 1984

    Google Scholar 

  15. Stanton A, Bywater RJ, Palmer GH: The use of tissue cage in calves to study distribution of antibiotics in interstitial fluid. Colloq INRA 8:263–266, 1982

    Google Scholar 

  16. Bunnett NW, Walsh JH, Debas HT, Kauffman GM, Golanska EM: Measurement of prostaglandin E1 in interstitial fluid from the dog stomach after feeding and indomethacin. Gastroenterology 85:1391–1398, 1983

    Google Scholar 

  17. Bunnett NW, Mogard M, Ortoff MS, Coubet HJ, Reeve JR Jr, Walsh JH: Catabolism of neurotensin in interstitial fluid of the rat stomach. Am J Physiol 246:G675-G682, 1984

    Google Scholar 

  18. Ruckebusch Y, Meirieu O, Von Ritter C, Blum AL: Measurement of monoamines and their metabolites in the interstitial fluid of the gut. J Pharmacol Methods 13:167–177, 1985

    Google Scholar 

  19. Eberts TJ, Samples RHB, Glick MR, Ellis GH: A simplified colorimetric micromethod for xylose in serum or urine, with phloroglucinol. Clin Chem 25:1440–1443, 1979

    Google Scholar 

  20. Barreiro MA, McKenna RD, Beck II: Determination of transit time in the human jejunum in the simple injection indicator-dilution technique. Am J Dig Dis 13:222–232, 1968

    Google Scholar 

  21. Eastwood MA, Robertson JA, Brydon WG, McDonald D: Measurement of water-holding properties of fibre and their faecal bulking ability in man. Br J Nutr 50:539–547, 1983

    Google Scholar 

  22. Bihler I, Kim ND, Sawh PC: Active transport ofl-glucose andd-xylose in hamster intestinein vitro. Can J Physiol Pharmacol 47:525–532, 1969

    Google Scholar 

  23. Levitt DG, Hakim AA, Lifson N: Evaluation of components of transport of sugars by dog jejunumin vivo. Am J Physiol 217:777–783, 1969

    Google Scholar 

  24. Caspary WF: On the mechanism ofd-xylose absorption from the intestine. Gastroenterology 63:531–532, 1972

    Google Scholar 

  25. McCrance RA, Madders. K: The comparative rate of absorption of sugars from the human intestine. Biochem J 24:795–804, 1930

    Google Scholar 

  26. Clemens ET, Stevens CE, Southworth M: Sites of organic acid production and pattern of digesta movement in the gastrointestinal tract of swine. J Nutr 105:759–768, 1975

    Google Scholar 

  27. Flourie B, Vidon N, Florent C, Bernier JJ: Effect of pectin on jejunal glucose absorption in man. Gut A911, 1982

  28. Holt S, Carter DC, Heading RC, Prescott LF, Tothill P: Effect of gel fiber on gastric emptying and absorption of glucose and paracetamol. Lancet 1:636–639, 1979

    Google Scholar 

  29. Tasman-Jones C, Hones AL, Owen RL: Jejunal morphological consequences of dietary fiber in rats. Gastroenterology 74:1102, 1978

    Google Scholar 

  30. Cassidy MM, Lightfoot FG, Vahouny GV: Dietary fiber, bile acids, and intestinal morphology.In Dietary Fiber in Health and Disease. GV Vahouny, D Kritchevsky (eds). New York, Plenum Press, 1982, pp 203–227

    Google Scholar 

  31. Lembcke B, Ebert R, Ptok M, Caspary WF, Creutzfeldt W, Schicha H, Emrich D: Role of gastrointestinal transit in the delay of absorption by viscous fiber (guar). Hepato-Gastroenterology 31:183–186, 1984

    Google Scholar 

  32. Johnson IT, Gee JM: Effect of gel-forming gums on the intestinal unstirred layer and sugar transportin vitro. Gut 22:398–403, 1981

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology, National Veterinary School, Toulouse, France

    C. Cherbut MS, O. Meirieu MS & Y. Ruckebusch DVM, DSc

Authors
  1. C. Cherbut MS
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. O. Meirieu MS
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Y. Ruckebusch DVM, DSc
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cherbut, C., Meirieu, O. & Ruckebusch, Y. Effect of diet on intestinal xylose absorption in dogs. Digest Dis Sci 31, 385–391 (1986). https://doi.org/10.1007/BF01311674

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01311674

Keywords

Search

Navigation