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Factors influencing susceptibility of laboratory rodents to infection with mouse adenovirus strains K87 and FL

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Summary

Weanling outbred mice were more than 500 times less susceptible to orally administered mouse adenovirus (MAdV) strain K87 than to MAdV-FL. Mouse susceptibility to MAdV-K87 was age-dependent but not obviously host genotype-dependent. Infant F344 rats were not susceptible to infection with either MAdV strain.

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Authors and Affiliations

  1. Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA

    Abigail L. Smith & S. W. Barthold

  2. Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA

    Abigail L. Smith

Authors
  1. Abigail L. Smith
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  2. S. W. Barthold
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Smith, A.L., Barthold, S.W. Factors influencing susceptibility of laboratory rodents to infection with mouse adenovirus strains K87 and FL. Archives of Virology 95, 143–148 (1987). https://doi.org/10.1007/BF01311342

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  • DOI: https://doi.org/10.1007/BF01311342

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