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Adenovirus 41 growth in semi-permissive cells shows multiple-hit kinetics

Summary

Adenovirus type 41 infection of semi-permissive Chang conjunctival cells, monitored by fluorescent focus assay, followed multiple-hit kinetics. In non-permissive human cells, type 41 showed infectivity with two-hit kinetics in the presence of type 2. Type 41 infectivity was seen to be directly proportional to input concentration (one-hit) only in 293 cells, a continuous human line expressing Ad 5 E 1 products.

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Tiemessen, C.T., Kidd, A.H. Adenovirus 41 growth in semi-permissive cells shows multiple-hit kinetics. Archives of Virology 110, 239–245 (1990). https://doi.org/10.1007/BF01311291

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  • DOI: https://doi.org/10.1007/BF01311291

Keywords

  • Infectious Disease
  • Human Cell
  • Human Line
  • Adenovirus Type
  • Input Concentration