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Electron microscopy and antigenic studies of uncharacterized viruses. I. Evidence suggesting the placement of viruses in familiesArenaviridae, Paramyxoviridae, orPoxviridae

Archives of Virology volume 108, pages 191–209 (1989)Cite this article

Summary

During approximately 35 years, investigators in various laboratories studying arbovirus ecology and epidemiology accumulated many virus isolates, more than 60 of which were not characterized or placed in taxa. By a combination of electron microscopic and antigenic studies we collected information sufficient to provisionally classify 60 isolates. Electron microscopic observations suggest that 20 are members of the virus familyBunyaviridae, 20Rhabdoviridae, 14Reoviridae, oneTogaviridae, oneParamyxoviridae (Mapuera virus, from a bat), and onePoxviridae (Yoka virus, from mosquitoes). Serologic studies provided evidence sufficient to place some of these viruses in recognized antigenic groups, within families and genera, and to establish new antigenic groups and taxa for others.

Three viruses were found to have morphologic and morphogenetic characteristics consistent with those of members of the familyArenaviridae: Quaranfil virus, a human pathogen, Johnston Atoll virus, isolated from birds and ticks, and Araguari virus, isolated from an opossum.

This, the first in a series of three papers, described methods used for these investigations and also presents descriptions of viruses provisionally placed in the familiesArenaviridae, Paramyxoviridae, orPoxviridae. Descriptions of viruses provisionally placed in familiesBunyaviridae andReoviridae are published in the second and third papers, respectively. Viruses of the familyRhabdoviridae have been described separately.

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Author notes

  1. H. G. Zeller

    Present address: Pasteur Institute, Cayenne, French Guiana

Authors and Affiliations

  1. Arbovirus Reference Branch, Division of Vector-Borne Viral Diseases, Center for Infectious Diseases, Centers for Disease Control, Public Health Service, US Department of Health and Human Services, Fort Collins, Colorado, U.S.A.

    H. G. Zeller, N. Karabatsos & Ch. H. Calisher

  2. Pasteur Institute, Dakar, Senegal

    J. -P. Digoutte

  3. Center for Infectious Diseases, Centers for Disease Control, Public Health Service, US Department of Health and Human Services, Atlanta, Georgia

    F. A. Murphy

  4. Yale Arbovirus Research Unit, School of Medicine, Yale University, New Haven, Connecticut, U.S.A.

    R. E. Shope

Authors
  1. H. G. Zeller
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  2. N. Karabatsos
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  3. Ch. H. Calisher
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  4. J. -P. Digoutte
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  5. F. A. Murphy
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  6. R. E. Shope
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Zeller, H.G., Karabatsos, N., Calisher, C.H. et al. Electron microscopy and antigenic studies of uncharacterized viruses. I. Evidence suggesting the placement of viruses in familiesArenaviridae, Paramyxoviridae, orPoxviridae . Archives of Virology 108, 191–209 (1989). https://doi.org/10.1007/BF01310934

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  • DOI: https://doi.org/10.1007/BF01310934

Keywords

  • Electron Microscopy
  • Infectious Disease
  • Microscopic Observation
  • Virus Isolate
  • Human Pathogen