Summary
Peripheral blood cultures from children showing symptoms of generic infectious disease have been examined for human herpesvirus-6 (HHV-6). Two HHV-6-related isolates have been obtained: one from a child for whom a clinical diagnosis of exanthema subitum has been made when a typical rash appeared, and one from a child in whom the infectious symptomatology has maintained the characters of nonspecific syndrome. All the syndrome diagnosed as exanthema subitum resulted as being associated with fresh infection by HHV-6-related virus.
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Portolani, M., Cermelli, C., Pietrosemoli, P. et al. Isolation of HHV-6-related virus from children affected by infectious syndrome. Archives of Virology 110, 143–149 (1990). https://doi.org/10.1007/BF01310711
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DOI: https://doi.org/10.1007/BF01310711