Summary
An in vitro foetal intestinal organ culture system was employed to determine the permissiveness of human intestinal cells for subgroup F adenovirus infection. Ad 40 and Ad 41 growth, monitored through group-specific hexon antigen production, was poor in comparison to that of Ad 2 in these cultures, further demonstrating their fastidious nature in most human cells. The low growth capability of these viruses in culture, in relation to their association with gastrointestinal disease is discussed.
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Tiemessen, C.T., Ujfalusi, M. & Kidd, A.H. Subgroup F adenovirus growth in foetal intestinal organ cultures. Archives of Virology 132, 193–200 (1993). https://doi.org/10.1007/BF01309853
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DOI: https://doi.org/10.1007/BF01309853