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Protein synthesis in cells infected by Chilo Iridescent Virus (Iridovirus, type 6)

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Summary

Synthesis of the polypeptides induced in CIV-infected cells was studied using radiolabelled methionine in a permissive cell line ofChoristoneura fumiferana.

Analysis of labelled cell extracts by high resolution polyacrylamide gel electrophoresis (PAGE) revealed the sequential appearance of at least 28 structural and non-structural polypeptides in permissive conditions. This was confirmed by analysis of protein synthesis in non-permissive cell lines ofLymantria dispar, Aedes albopictus or by the use of protein, RNA and DNA synthesis inhibitors in the permissive cell line.

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Barray, S., Devauchelle, G. Protein synthesis in cells infected by Chilo Iridescent Virus (Iridovirus, type 6). Archives of Virology 86, 315–326 (1985). https://doi.org/10.1007/BF01309835

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