Archives of Virology

, Volume 140, Issue 1, pp 165–172 | Cite as

Protection against hantavirus infection by dam's immunity transferred vertically to neonates

  • K. Dohmae
  • Y. Nishimune
Brief Report


Antibodies to hantavirus, Seoul type B-1 strain, vertically transferred to rat neonates prevented lethal as well as persistent infection. When relatively high titer viruses were inoculated into neonates, the mother's antibodies protected all the neonates from lethal virus infection. However, the antibodies could not protect all of the neonates from persistent infection but only half of them underwent persistent infection. The other half was completely cured but also became persistently infected when rechallenged with the active viruses after reaching maturity.


Infectious Disease Virus Infection High Titer Titer Virus Persistent Infection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • K. Dohmae
    • 1
  • Y. Nishimune
    • 1
  1. 1.Research Institute for Microbial DiseasesOsaka UniversityOsakaJapan

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