Skip to main content
SpringerLink
Log in

Properties of host and virus which influence defective interfering virus mediated-protection of mice against Semliki Forest virus lethal encephalitis

  • Brief Report
  • Published:
Archives of Virology Aims and scope Submit manuscript

Summary

Variation of the mouse strain, the amount of defective interfering (DI) virus and the amount of infectious Semliki Forest virus (SFV) are all factors which affect the efficiency with which DI SFV prevents the SFV-mediated lethal encephalitis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Barrett, A. D. T., Crouch, C. F., Dimmock, N. J.: Assay of defective-interfering Semliki Forest virus by the inhibition of synthesis of virus-specified RNAs. J. gen. Virol.54, 273–280 (1981).

    Google Scholar 

  2. Crouch, C. F., Mackenzie, A., Dimmock, N. J.: The effect of defective-interfering Semliki Forest virus on the histopathology of infection with virulent Semliki Forest virus in mice. J. Inf. Dis.146, 411–416 (1982).

    Google Scholar 

  3. Dimmock, N. J., Kennedy, S. I. T.: Prevention of death in Semliki Forest virus-infected mice by administration of defective interfering Semliki Forest virus. J. gen. Virol.39, 231–242 (1978).

    Google Scholar 

  4. Doyle, M., Holland, J. J.: Prophylaxis and immunization in mice by use of virus-free defective T particles to protect against intracerebral infection by vesicular stomatitis virus. Proc. Nat. Acad. Sci. U.S.A.70, 2105–2108 (1973).

    Google Scholar 

  5. Holland, J. J., Doyle, M.: Attempts to detect homologous autointerferencein vivo with influenza virus and vesicular stomatitis virus. Inf. Imm.7, 526–531 (1973).

    Google Scholar 

  6. Holland, J. J., Kennedy, S. I. T., Semler, B. L., Jones, C. L., Roux, L., Grabau, E. A.: Defective interfering RNA viruses and the host cell response. In:Fraenkel-Conrat, H., Wagner, R. R. (eds.), Comprehensive Virology, Vol. 15, 137–192. New York: Plenum Press 1980.

    Google Scholar 

  7. Huang, A. S., Baltimore, D.: Defective viral particles and viral disease processes. Nature (London)226, 325–327 (1970).

    Google Scholar 

  8. Huang, A. S., Baltimore, D.: Defective interfering animal viruses. In:Fraenkel-Conrat, H., Wagner, R. R. (eds.), Comprehensive Virology, Vol. 10, 73–116. New York: Plenum Press 1977.

    Google Scholar 

  9. Perrault, J.: Origin and replication of defective interfering particles. Curr. Top. Micro. Imm.93, 151–207 (1981).

    Google Scholar 

  10. Stollar, V.: Defective interfering alphaviruses. In:Schlesinger, R. W. (ed.), The Togaviruses: Biology, Structure, Replication, 427–457. New York: Academic Press 1980.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biological Sciences, University of Warwick, Coventry, United Kingdom

    A. D. T. Barrett & N. J. Dimmock

Authors
  1. A. D. T. Barrett
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. J. Dimmock
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Barrett, A.D.T., Dimmock, N.J. Properties of host and virus which influence defective interfering virus mediated-protection of mice against Semliki Forest virus lethal encephalitis. Archives of Virology 81, 185–188 (1984). https://doi.org/10.1007/BF01309308

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01309308

Keywords

Search

Navigation