This paper reports the results of a multicenter prospective study of 188 consecutive patients affected by gastric ulcer, verified by endoscopy, in whom the frequency of a mycotic infection of the lesion was evaluated as well as the eventual influence of such pathology on the efficiency of medical treatment, the healing rate, and the healing time. A mycotic infection, defined as penetration of the periulcerous mucosa by the fungi, was found in only 13 patients (6.9%). No significant differences were found in the healing rate and helaing time among these patients treated with H2-receptor antagonists and a control group of 43 matched gastric ulcer patients treated in the same period with the same therapy. It would appear from the data that mycotic infections of the gastric ulcer do not modify the efficiency of medical treatment.
This is a preview of subscription content, access via your institution.
Buy single article
Instant access to the full article PDF.
Price includes VAT (USA)
Tax calculation will be finalised during checkout.
Odds FC: Ecology and epidemiology ofCandida.In Candida and Candidiasis. FC Odds (ed). Leicester, Leicester University Press, 1979, p 50–74
Cohen R, Roth FJ, Delgrado E, Ahearn DG, Kalser MH: Fungal flora of the normal human small and large intestine. N Engl J Med 280:638–641, 1969
Stone HH: Studies in the pathogenesis, diagnosis and treatment ofCandida sepsis in children. J Pediatr Surg 9:127–133, 1974
Eras P, Goldstein MJ, Sherlock P:Candida infection of the gastrointestinal tract. Medicine 51:367–379, 1972
Moulinier B, Lambert R, Grenier-Boley P, Bruhiére J: Les mycoses de l'oesophage. Nouv Press Med 1:2629–2632, 1972
Minoli G, Terruzzi V, Butti G, Frigerio G, Rossini A: Gastric candidiasis: An endoscopic and histological study in 26 patients. Gastrointest Endosc 28:59–61, 1982
Scott BB, Jenkins D: Gastro-oesophageal candidiasis. Gut 23:137–139, 1982
Kodsi BE, Wickremesinghe PC, Kozinn PJ, Iswara K, Goldberg PK:Candida esophagitis—a prospective study of 27 cases. Gastroenterology 71:715–719, 1976
Vilotte J, Toutoungi M, Coquillard A: Ulcères gastriques colonisès parCandida. Caractèristiques cliniques et biologiques. Nouv Press Med 10:1471–1474, 1981
Katzenstein AA, Maksem J: Candida infection of gastric ulcers. Am J Clin Pathol 71:137–141, 1979
Nicholls PE, Henry K: Gastritis and cimetidine: A possible explanation. Lancet 1:1905, 1979
Eugene C, Defrance R, Quevauvilliers J: Candidose et ulcère gastrique apparus suns traitement par la cimetidine. Nouv Press Med 10:2665, 1981
Toala P, Schroeder SA, Daly AV, Finland M:Candida at Boston City Hospital. Arch Intern Med 126:983–989, 1970
Brooks JR, Smith FR, Pearse B: Bacteriology of the stomach immediately following vagotomy. Ann Surg 179:859–862, 1974
Cipollini F, Altilia F: Candidiasis of the small intestine. Gastroenterology 81:823, 1981
Bayle E, Pelle B, Halgrain JP, Tran-Ky K, Moussalier K: Perforation duodènale àCandida albicans. Nouv Press Med 8:3674–3676, 1979
Gotlieb-Jensen K, Andersen J: Occurrence ofCandida in gastric ulcer. Singificance for the healing process. Gastroenterology 85:535–537, 1983
About this article
Cite this article
Di Febo, G., Miglioli, M., Calò, G. et al. Candida albicans infection of gastric ulcer frequency and correlation with medical treatment. Digest Dis Sci 30, 178–181 (1985). https://doi.org/10.1007/BF01308206
- Public Health
- Medical Treatment
- Gastric Ulcer
- Candida Albicans