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A simple new method for the controlled constriction of the renal and other arteries in small laboratory animals during chronic experiments

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Summary

The author proposed a new, simple technique of controlled constriction of the renal and other arteries. This method may be used for creating a model of diseases (hypertension—renal and coarctation, stenosis of the aorta), as well as for the study of collateral circulation. The method may be conveniently used for experiments both on small and large laboratory animals. It consists in placing a spiral with a set diameter upon the vessel, which constricts and becomes equal in diameter to the spiral. The method was successfully tested on rats in experiments with induction of renal hypertension by producing stenosis of renal arteries.

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Authors and Affiliations

  1. Department of Pathophysiology of the First I. M. Sechenov Order of Lenin, Institute of Medicine, Moscow

    A. Kh. Kogan

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  1. A. Kh. Kogan
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Kogan, A.K. A simple new method for the controlled constriction of the renal and other arteries in small laboratory animals during chronic experiments. Bull Exp Biol Med 51, 112–115 (1961). https://doi.org/10.1007/BF01306892

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  • DOI: https://doi.org/10.1007/BF01306892

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