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Expectant management as an option for men with stage T1c prostate cancer: a preliminary study

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Abstract

The outcome of patients selecting observation of clinical stage T1c prostate cancer is unknown. A total of 101 men with clinical stage T1c prostate cancer were evaluated, counseled, and monitored in a standard fashion. Altogether, 27 men who elected observation were older and had greater co-morbidity but similar tumor characteristics as compared with 74 men who elected radical prostatectomy. In all, 9 men demonstrated clinical or biochemical evidence of progression after a mean follow-up of 23 months; 4 men who underwent radical prostatectomy had specimen-confined disease and undetectable post-operative levels of PSA. Observation appears to be a viable option for some men with clinical stage T1c prostate cancer.

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Authors and Affiliations

  1. Division of Urology, Department of Surgery, University of North Carolina Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA

    James L. Mohler, Bernadette T. Williams & John A. Freeman

  2. Division of Urology, University of North Carolina, CB #7235, Burnett-Womack Building, 27599-7235, Chapel Hill, NC, USA

    J. L. Mohler

Authors
  1. James L. Mohler
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  2. Bernadette T. Williams
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  3. John A. Freeman
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  4. J. L. Mohler
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Corresponding author

Correspondence to J. L. Mohler.

Additional information

This study was supported by a University of North Carolina Lineberger Comprehensive Cancer Center clinical research award

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Mohler, J.L., Williams, B.T., Freeman, J.A. et al. Expectant management as an option for men with stage T1c prostate cancer: a preliminary study. World J Urol 15, 364–368 (1997). https://doi.org/10.1007/BF01300184

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  • DOI: https://doi.org/10.1007/BF01300184

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