Summary
Fourteen years after kidney transplantation and following protracted rejection of the transplant, a patient developed abdominal pain, fever, and leukocytosis. Ultrasound demonstrated a pericolic abscess, and barium enema a deformity of the ascending colon suggesting malignant growth. Colonoscopy showed ulcerative and necrotic lesions of the cecum, and colonic carcinoma was suspected. At surgery, a granulomatous inflammatory reaction with fibrosis involving the kidney transplant and cecum was found. Histological examination revealed ulcerations secondary to ischemic colitis, but no malignancy.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Williams LF Jr: Vascular insufficiency of the bowels. Dis Mon August 1970
Fagin RR, Kirsner JB: Ischemic diseases of the colon. Adv Intern Med 17:343–362, 1971
Ottinger LW, Darling RC, Nathan MJ, Linton RR: Left colon ischemia complicating aorto-iliac reconstruction. Causes, diagnosis, management and prevention. Arch Surg 105:841–846, 1972
Ferarri BT, Ray JE, Robertson HD, Bonau RA, Gathright JB Jr: Colonic manifestations of collagen vascular disease. Dis Colon Rectum 23:473–477, 1980
Bandyk DF, Florence MG, Johansen KH. Colon ischemia accompanying ruptured aortic aneurysm. J Surg Res 30:297–303, 1981
Seagesser F, Sandblom P: Ischemic lesions of the distended colon. A complication of obstructive colorectal cancer. Am J Surg 129:309–315, 1975
Whitehouse GH, Walt J: Ischemic colitis associated with carcinoma of the colon. Gastrointest Radiol 2:31–35, 1977
Margolis DM, Etheredge EE, Garza-Garza R: Ischemic bowel disease following bilateral nephrectomy or renal transplant. Surgery 82:667–673, 1971
Powis SJA, Barnes AD, Dawson-Edwards P, Thompson H: Ileocolonic problems after cadaveric renal transplantation. Br Med J 1:99–101, 1972
Penn I, Brettschneider L, Simpson K, Martin A, Starzl LF: Major colonic problems in human homotransplant recipients. Arch Surg 100:61, 1970
Perloff LJ, Chon H, Petrella EJ, Grossman RA, Barker CF: Acute colitis in the renal allograft recipient. Ann Surg 183:77–83, 1976
Kilpatrick ZM, Silverman JF, Betancourt E, Farman J, Lawson JP: Vascular occlusion of the colon and oral contraceptives: Possible relation. N Engl J Med 278:438–440, 1968
Cinqualbre J: Chronic ischaemia of the gut.In Textbook of Gastroenterology. IAD Bouchier, RN Allan, HJF Hodgson, MRB Keighley (eds). London, Baillière Tindall, 1984, pp 274–278
Reeders JWAJ, Tytgat GNJ, Rosenbusch G, Gratama S: Ischaemic Colitis. Boston, Martinus Nijhoff, 1984, pp 7–8
Cinqualbre J, Wenger JJ, Kieny R: Infarctus mésentérique: conduite à tenir. Rev Prat 31:2083–2105, 1981
Author information
Authors and Affiliations
Additional information
This work was supported by the Swedish Medical Research Council (No. 7916) and the Karolinska Institute.
Rights and permissions
About this article
Cite this article
Hellström, P.M., Rubio, C., Odar-Cederlöf, I. et al. Ischemic colitis of the cecum after renal transplantation masquerading as malignant disease. Digest Dis Sci 36, 1644–1648 (1991). https://doi.org/10.1007/BF01296410
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01296410