Summary
We report the case of a patient with carbamazepine-induced cholestasis in whom histologic examination showed acute cholangitis. This type of lesion broadens the spectrum of carbamazepine-induced liver injury which also includes granuloma and hepatocellular necrosis. Its association with marked hypereosinophilia suggests that carbamazepine may causse acute cholangitis through an immunoallergic mechanism.
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Larrey, D., Hadengue, A., Pessayre, D. et al. Carbamazepine-induced acute cholangitis. Digest Dis Sci 32, 554–557 (1987). https://doi.org/10.1007/BF01296041
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DOI: https://doi.org/10.1007/BF01296041