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Effects of nutrients on gastrointestinal motility and gastric emptying after distal gastrectomy with Roux-Y gastrojejunostomy in dogs

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Abstract

The aim of the study was to clarify whether nutrients are still capable of slowing gastric emptying following Roux-Y gastrectomy, as in normal dogs. Gastrointestinal motility and gastric emptying of acaloric and nutritive meals with different viscosities were measured in normal dogs and after a two-thirds Roux-Y gastrectomy. In gastrectomized dogs low-viscosity nutritive meals emptied unduly rapidly in an initial phase, although the frequency and spread of contractions, ie, the propulsive activity of the jejunal Roux limb were diminished. A slow emptying rate during the following period was due to a long-lasting inhibition of gastric and jejunal motility. Medium-viscosity nutritive meals emptied in gastrectomized dogs as slowly as in normal animals, but this effect was primarily caused by the meal viscosity and only secondarily by the nutrients. It is concluded that following Roux-Y gastrectomy a regulation of gastric emptying is preserved; however, the onset of an effective control is delayed, resulting in a rapid initial emptying of low-viscosity meals.

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Authors and Affiliations

  1. Institute of Zoophysiology, University of Hohenheim, Garbenstr. 30, D-7000, Stuttgart 70, Federal Republic of Germany

    Hans-Jörg Ehrlein, Gert Thoma, Oliver Keinke, Christian Tsiamitas & Volker Schumpelick

  2. Clinic of Surgery, University of Hamburg, Federal Republic of Germany

    Hans-Jörg Ehrlein, Gert Thoma, Oliver Keinke, Christian Tsiamitas & Volker Schumpelick

Authors
  1. Hans-Jörg Ehrlein
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  2. Gert Thoma
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  3. Oliver Keinke
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  4. Christian Tsiamitas
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  5. Volker Schumpelick
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Additional information

Studies were supported by the Deutsche Forschungsgemeinschaft grant Eh 64/3-1.

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Ehrlein, HJ., Thoma, G., Keinke, O. et al. Effects of nutrients on gastrointestinal motility and gastric emptying after distal gastrectomy with Roux-Y gastrojejunostomy in dogs. Digest Dis Sci 32, 538–546 (1987). https://doi.org/10.1007/BF01296038

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  • DOI: https://doi.org/10.1007/BF01296038

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