Skip to main content
Log in

Contributions to the treatment of tracer distribution equations in multicompartmental systems

  • Published:
Biophysik Aims and scope Submit manuscript

Summary

A tracer kinetic method is outlined for the treatment of multicompartmental non steady-state systems. Metabolic rates are considered as consisting of two components: one of them (exchange) is balanced by a reverse process of the same rate, and the other (transport) results in concentration change. Assuming the transport rates to be known, the method allows of excluding a lot of logically possible compartmental models as inconsistent with the experimental data. Thus the real compartment structure of the system can be approached.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Branson, H.: The mathematical treatment of metabolic processes. In: Künstliche radioaktive Isotope in Physiologie, Diagnostik und Therapie, Vol. I, p. 596, (Schwiegk, H., Turba, F., Eds.). Berlin-Göttingen: Heidelberg: Springer 1961.

    Google Scholar 

  2. Brownell, G. L., Berman, M., Robertson, J. S.: Nomenclature for tracer kinetics. Internat. J. appl. Radiat.19, 249–262 (1968).

    Google Scholar 

  3. Latzkovits, L., Szentistványi, I., Fajszi, Cs.: Tracer kinetic analysis of phosphate incorporation into erythrocytesin vitro, I. Acta biochim. biophys. Acad. Sci. hung.7, 55–66 (1972).

    Google Scholar 

  4. Reiner, J. M.: Study of metabolic turnover rates by means of isotopic tracers, I, II. Arch. Biochem. Biophys.46, 53–79, 80–99 (1953).

    Google Scholar 

  5. Solomon, A. K.: Compartmental methods of kinetic analysis. In; Mineral metabolism, Vol. I, Part A, (Comar, C. L., Bronner, F., Eds.), p. 119. New York: Academic Press 1960.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fajszi, C., Latzkovits, L. Contributions to the treatment of tracer distribution equations in multicompartmental systems. Biophysik 9, 64–69 (1972). https://doi.org/10.1007/BF01293480

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01293480

Keywords

Navigation