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28. Hepatologische Gesichtspunkte

Postoperative syndromes of liver and portal vein: Hepatological aspects

  • B. Wissenschaftliches Programm
  • I. Hauptthemen mit Rundgesprächen C. Gastrointestinale Chirugie - postoperative Syndrome. Pathogenese, Diagnostik, Therapie c)Postoperative Syndrome an Leber un Pfortader
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Summary

After liver resections hepatocellular failure is one of the most severe postoperative syndromes. The risk of liver failure should be evaluated preoperatively by quantitative tests of hepatic function (e. g., galactose elimination capacity, sulfobromophthalein elimination, aminopyrine breath test). Treatment of liver failure, besides supportive therapy and the usual therapy for hepatic coma, includes the administration of special amino acid mixtures. After shunt operations portasystemic encephalopathy is the most important postoperative syndrome. So far it is not possible to prevent this syndrome by patient selection or special methods of shunt surgery. Effective therapeutic modalities are available, however.

Zusammenfassung

Nach Leberresektionen ist die Leberzellinsuffizienz eines der schwerwiegendsten postoperativen Syndrome. Das Risiko eines Leberversagens sollte mittels quantitativer Tests der Leberfunktion (z. B. Galaktoseeliminationskapazität, Bromsulphthaleinelimination, Aminopyrin-Atemtest) präoperativ erfaßt werden. Die Behandlung des Leberversagens umfaßt neben einer unterstützenden Therapie und neben der üblichen Komabehandlung auch die Gabe spezieller Aminosäurengemische. Nach Shuntoperationen ist die portosystemische Encephalopathie das wichtigste postoperative Syndrom. Bisher ist es nicht möglich, dieses Syndrom durch Patientenselektion oder durch spezielle Operationsmethoden zu verhindern. Für seine Behandlung stehen jedoch wirksame Therapieverfahren zur Verfügung.

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Literatur

  1. Stone, H. H.: Preoperative and postoperative care. Surg. Clin. North Am.57, 409 (1977)

    Google Scholar 

  2. Akovbiantz, A., Schmid, M., Schmid, E.: Postoperative syndromes after liver surgery. Clin. Gastroenterol.8, 471 (1979)

    Google Scholar 

  3. Tygstrup, N.: Determination of the hepatic elimination capacity (Lm) of galactose by single injection. Scand. J. Clin. Lab. Invest. [Suppl. 95]18, 118 (1966)

    Google Scholar 

  4. Häcki, W., Bircher, J., Preisig, R.: A new look at the plasma disappearance of sulphobromophthalein (BSP): Correlation with the BSP transport maximum and the hepatic plasma flow in man. J. Lab. Clin. Med.88, 1019 (1976)

    Google Scholar 

  5. Bircher, J., Küpfer, A., Gikalov, I., Preisig, R.: Aminopyrin demethylation measured by breath analysis in cirrhosis. Clin. Pharmacol. Ther.20, 484 (1976)

    Google Scholar 

  6. Paumgartner, G.: Methoden zur Erfassung der splanchnischen Hdmodynamik. Verb. Dtsch. Ges. Inn. Med.82, 148 (1976)

    Google Scholar 

  7. Burchell, A. R., Moreno, H. H., Panke, W. F., Nealon, T. F.: Hepatic artery flow improvement after portacaval shunt: A single hemodynamic clinical correlate. Ann. Surg.184, 289 (1976)

    Google Scholar 

  8. Galambos, J. T., Warren, W. D., Rudman, D., Smith, R. B., Salam, A. A.: Selective and total shunts in the treatment of bleeding varices. A randomized trial. N. Engl. J. Med.295, 1089 (1976)

    Google Scholar 

  9. Reichle, F. A., Fahmy, W. F., Golsorkhi, M.: Prospective comparative clinical trial with distal splenorenal and mesocaval shunts. Am. J. Surg.137, 13 (1979)

    Google Scholar 

  10. Langer, B., Stone, R. M., Patel, S. C., Colapinto, R. F.: A prospective randomized trial of the selective distal splenorenal shunt. Surg. Gynecol. Obstet.150, 45 (1980)

    Google Scholar 

  11. Resnick, R. H., Atterbury, C. E., Grace, N. D., Conn, H. O.: Distal splenorenal shunt (DSRS) v.s. portalsystemic shunt (PSS): Current status of a controlled trial. Gastroenterology77, 1733 (1979)

    Google Scholar 

  12. Conn, H. O., Lieberthal, M. M.: The hepatic coma syndromes. Baltimore: Williams & Wilkins 1979

    Google Scholar 

  13. Morgan, M. Y., Jakobovits, A. W., James, I. M., Sherlock, S.: Successful use of bromocriptine in the treatment of chronic hepatic encephalopathy. Gastroenterology78, 663 (1980)

    Google Scholar 

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Paumgartner, G. 28. Hepatologische Gesichtspunkte. Langenbecks Arch Chiv 352, 145–147 (1980). https://doi.org/10.1007/BF01291989

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  • DOI: https://doi.org/10.1007/BF01291989

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