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Multi-modality mapping of motor cortex: comparing echoplanar BOLD fMRI and transcranial magnetic stimulation

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  • Basic Neurosciences and Genetics
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Summary

Multiple non-invasive methods of imaging brain function are now available for presurgical planning and neurobiological research. As these new methods become available, it is important to understand their relative advantages and liabilities, as well as how the information gained compares across different methods. A current and future trend in neurobiological studies as well as presurgical planning is to combine information from different imaging techniques. Multi-modal integration may perhaps give more powerful information than each modality alone, especially when one of the methods is transcranial magnetic stimulation (TMS), with its ability to non-invasively activate the brain. As an initial venture in cross comparing new imaging methods, we performed the following 2 studies, locating motor cortex with echoplanar BOLD fMRI and TMS. The two methods can be readily integrated, with concurring results, although each have important limitations.

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Author notes

  1. M. S. George

    Present address: Department of Radiology, Medical University of South Carolina, USA

Authors and Affiliations

  1. Department of Psychiatry, Medical University of South Carolina, USA

    D. R. Roberts, A. M. Speer & M. S. George

  2. Department of Radiology, Medical University of South Carolina, USA

    D. R. Roberts, D. J. Vincent, D. E. Bohning, J. Cure & J. Young

  3. Department of Neurology, Medical University of South Carolina, USA

    M. S. George

  4. Psychiatry Department, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC, USA

    M. S. George

Authors
  1. D. R. Roberts
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  2. D. J. Vincent
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  3. A. M. Speer
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  4. D. E. Bohning
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  5. J. Cure
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  6. J. Young
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  7. M. S. George
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Roberts, D.R., Vincent, D.J., Speer, A.M. et al. Multi-modality mapping of motor cortex: comparing echoplanar BOLD fMRI and transcranial magnetic stimulation. J. Neural Transmission 104, 833–843 (1997). https://doi.org/10.1007/BF01285552

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  • DOI: https://doi.org/10.1007/BF01285552

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