The propagation of poliomyelitis virus and some other viruses in cultures of transplantable mouse carcinoma and sarcoma cells

Summary

Cultures of transplantable mammary carcinoma and tail root sarcoma cells of mice were initiated and maintained by serial passage. The 3 types of poliomyelitis virus, unidentified viruses from human stools, herpes and vaccinia virus multiplied in these cultures, producing a cytopathogenic effect similar to that in HeLa cell cultures. The mouse tumor tissue cultures proved useful for the isolation and serological identification of poliomyelitis virus from human stools.