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The effect of pre- and postnatal undernutrition on axonal growth and myelination of central motor fibers

A morphometric study on rat cortico-spinal tract

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Summary

A morphometric study of the axon circumference and myelin sheath thickness in the rat corticospinal tract was undertaken to establish the effect of pre- and postnatal undernutrition and subsequent nutritional rehabilitation. Both axonal growth and myelin deposition were affected by undernutrition. Rats subjected to postnatal nutritional rehabilitation revealed a catch-up in axonal growth; whereas the process of myelination remained affected.

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Sima, A., Sourander, P. The effect of pre- and postnatal undernutrition on axonal growth and myelination of central motor fibers. Acta Neuropathol 42, 15–18 (1978). https://doi.org/10.1007/BF01273261

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  • DOI: https://doi.org/10.1007/BF01273261

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