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Interrelationship between lactate and cardiac fatty acid metabolism

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Abstract

This overview is presented, in the main, to summarize the following aspects of lactate and cardiac fatty acid metabolism:

  1. 1.

    The utilization of exogenous carbohydrates and fatty acids by the heart.

  2. 2.

    The competition between lactate and fatty acids in cardiac energy metabolism.

  3. 3.

    The effect of lactate on endogenous triacylglycerol homeostasis.

  4. 4.

    Lactate-induced impairment of functional recovery of the post-ischemic heart.

  5. 5.

    The effect of lactate on lipid metabolism in the ischemic and post-ischemic heart.

  6. 6.

    The consequences of hyperlactaemia for cardiac imaging.

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Authors and Affiliations

  1. Department of Physiology, Cardiovascular Research Institute Maastricht, University of Limburg, Maastricht, The Netherlands

    Ger J. van der Vusse & Monique J. M. de Groot

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  1. Ger J. van der Vusse
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  2. Monique J. M. de Groot
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van der Vusse, G.J., de Groot, M.J.M. Interrelationship between lactate and cardiac fatty acid metabolism. Mol Cell Biochem 116, 11–17 (1992). https://doi.org/10.1007/BF01270563

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  • DOI: https://doi.org/10.1007/BF01270563

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