Summary
Sulfur metabolism was traced in experimental investigations on rats, and the importance of the method for neutralizing sulfur dioxide with ammonia was estimated.
The animals were exposed to S35O2 by means of inhalation, and radioactivity in several organs at different periods of exposure was traced.
Sulfur incorporation into proteins and mucopolysaccharides, as well as elimination of isotope with urine and feces at different periods of time after exposure, were also determined. The second group of animals was exposed to the products of S35O2 neutralized by ammonia; after performing identical investigations it was found that the use of ammonia to neutralize sulfur dioxide in the air decreased the amount of sulfur which could pass into the organism through the breathing of air contaminated by SO2. The use of S35O2 neutralized by ammonia brings about a faster elimination of sulfur from the organism.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Amdur, M.O.: Toxicologic appraisal of perticulate matter exides of sulfur and sulfuric acid. J.Air Poll. Control Assoc.19, 638 (1969)
Balchum, O.J., Dybicki, J., Meneely, G.R.: The dynamics of sulfur dioxide inhalation (absorption, distribution and retention). Arch.Ind. Health21, 564 (1960)
Balchum, O.J., Dybicki, J., Meneely, G.R.: Pulmonary resistance and compliance with concurrent radioactive sulfur distribution in dogs breathing S35O2. J.Appl.Physiol.15, 62 (1960)
Bystrova, T.A.: Effects of sulfur dioxide. Studies with the use of labelled atoms [Russian]. Gig. i Sanit.20, 30 (1957)
Di Ferrante, N., Rich, C.: The determination of acid mucopolysaccharides in urine. J.Lab.Clin.48, 491 (1956)
Frank, N.R., Yoder, R.E., Yokoyama, E., Speizer, F.E.: The diffusion of SO2 from tissue fluids into the lungs following exposure of dogs to SO2. Health Physics13, 31 (1967)
Kośmider, St.: The effects of some gaseous atmospheric pollutants on the development of the respiratory organs diseases [Polish]. Pol. Arch.Med.Wewn.5, 417 (1973)
Kośmider, St., Chruściel, R., Dróżdż, M., Luciak, M., Ludyga, K., Szyguł/la, J., Szymaniec, J., Tyczyński, Z., Zajusz, K.: Method of binding of SO2 with ammonia in prolonged experiment Polish]. Medycyna Pracy1, 47 (1972)
Lewis, T.R., Moorman, W.J., Ludmann, M.S., Campbell, K.J.: Toxicity of long-term exposure to oxides of sulfur. Arch.Environ.Health26, 16 (1973)
Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randall, R.J.: Protein measurement with the Follin phenolreagent. J.Biol.Chem.193, 265 (1951)
Yokoyama, E., Yoder, R.E., Frank, N.R.: Distribution of S35 in the blood and its excretion in urine of dogs exposed to S35O2. Arch. Environ.Health22, 389 (1971)
Author information
Authors and Affiliations
Additional information
This work was supported by the Environmental Protection Agency USA, Project No. 5-533-1.
Rights and permissions
About this article
Cite this article
Kośmider, S., Janiec, W. & Chruściel, R. Sulfur (S35) metabolism in rats exposed to 535O2 contained in the air with simultaneous use of the method of (S35O2) binding by ammonia. Int. Arch Occup Environ Heath 35, 67–79 (1975). https://doi.org/10.1007/BF01266327
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01266327