Summary
Between 1980 and 1987 a total of 17 patiens were operated upon in curative intention of the Non-Hodgkin-Lymphoma of the stomach at our surgical department. Ten of these patients were within Ann-Arbor-Stage I, four within stae II/1 and the other three within stage II/2. In six cases we found low-malignant and in the other 11 cases high-malignant tumors. One patient died postoperatively after a myocardial infarction, one female died four months postoperatively in spite of chemotherapy of the disease. 15 patients (94%) are still alive today without any new symptoms of the disease, within a median average observation time of 40.6 months.
Zusammenfassung
Von 1980–1987 wurden an der Chirurgischen Abteilung des Evangelischen Krankenhauses Köln-Kalk 17 Patienten mit einem primären Non-Hodgkin-Lymphom des Magens unter kurativer Zielsetzung operiert. 10 Patienten befanden sich im Ann-Arbor-Stadium I, 4 im Stadium II/1 und 3 im Stadium II/2. 6 Patienten hatten Tumoren mit niedrigem, 11 mit hohem Malignitätsgrad. Ein Patient verstarb postoperativ an einem Herzinfarkt. Eine Patientin mit dem Stadium II/2 erlag 4 Monate nach dem Eingriff trotz Chemotherapie ihrer Erkrankung. 15 Patienten (94%) leben z. Zt. ohne erneute Krankheitsmanifestationen bei einer medianen Beobachtungszeit von 40,6 Monaten.
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Literatur
Adkins RB, Scott HW, Sawyers JL (1987) Gastrointestinal lymphoma and sarcoma. Ann Surg 205:625–633
Allmendiger G, Buchelt I, Lorenz H, Schmidt P (1982) Non-Hodgkin-Lymphome des Gastrointestinaltraktes. Therapie 32:3623
Altenberger Seminar (1987) Gastrointestinale Lymphome. 2-4.7. 1987
Aozasa K, Tsujimoto M, Inoue A, Nakagawa K, Hana J, Kurata A, Nosaka J (1985) Primary gastrointestinal lymphoma. Oncology 42:97–103
Bonadonna G, Tattuada A, Nofardini S, Milan F, Banfi A (1979) Combined radiotherapy in localized Non-Hodgkin's lymphomas, 5-years results of a randomized study. In: Jones SE, Salmon SE (eds) Adjuvant therapy of cancer II. Grune and Stratton, New York
Bongartz G, Peters PE (1987) Klinische Stadieneinteilung maligner Lymphome. Radiologe 27:355–362
Brittinger G, Musshoff K, Bremer K, Meuser P (1980) Grundlagen und allgemeine Probleme der Therapie der Non-Hodgkin-Lymphome. Internist 21:493–501
Brooks JJ, Enterline HT (1983) Primary gastric lymphomas. Cancer 51:701
Contreary K, Nance FC, Becker WF (1980) Primary lymphoma of the gastrointestinal tract. Ann Surg 191: 593–598
Dawson IMP, Cornes JS, Morson BC (1961) Primary malignant lymphoid tumors of the intestinal tract. Br J Surg 49:80–89
Dewitz H v (1980) Befall von Magen, Dünndarm und Kolon bei lymphozytären wohldifferenzierten malignen Lymphomen. Röntgen-Bl 33:199–202
Dragosics B, Bauer P, Radaskiewicz T (1985) Primary gastrointestinal Non-Hodgkin-lymphomas. Cancer 55:1060
Dworkin B, Lightdale CJ, Weingard DN (1982) Primary gastric lymphoma: a review of 50 cases. Dig Dis Sci 27:986–992
Fitsch DD, Wilson JAP (1985) Primary gastrointestinal lymphoma. South Med J 78:909–913
Fleming ID, Mitchell S, Dilawari RA (1982) The role of surgery in the management of gastric lymphoma. Cancer 49:1135–1141
Hajnos G, Pirovino M, Rüttner JR (1976) Extranoduläre Manifestation generalisierter maligner Lymphome. Schweiz Med Wochenschr 106:234–239
Herrmann R, Panahon PM, Barcos MP, Walsh D, Stutzman L (1980) Gastrointestinal involvement in NonHodgkin's lymphoma. Cancer 56:215–222
Hertzer NR, Hoerr SO (1976) An interpretive review of lymphoma of the stomach. Surg Gynecol Obstet 143:113–124
Kimmig G, Kober B, Weber M (1984) Ultraschall in der Diagnostik maligner Lyphome. Röntgen-Bl 37:57–60
Lorenz R, Zankovich R, Mödder U, Beyer D (1987) Primäres malignes Lymphom des Magens. Fortschr Röntgenstr 147:156–160
Megibow AJ, Bathazar EJ, Naidich DP, Bosiak MA (1983) Computed tomography of the gastrointestinal lymphoma. Am J Roentgenol 141:541–547
Meyer HJ, Huchzermeyer H, Ostertag H, Diehl V, Hassenstein E, Pichelmayr R (1981) Indikation und Behandlung der chirurgischen Therapie bei nicht epithelialen, primären Malignomen des Magens. Onkologie 3:168–172
Mitrou M, McKelvey EM (1978) Review of Cop-Hop combination chemotherapy in malignant lymphoma. Proc AACR, ASCO 19:415
Mokros W, Wilgeroth Ch, Schwenke E, Kettner E, Spormann H (1985) Diagnostische und therapeutische Probleme des primären Non-Hodgkin-Lymphoms des Magens. Z Ges Inn Med 40:117–121
Musshoff K, Schmidt-Vollmer H (1975) Prognosis of Non-Hodgkin's lymphomas with special emphasis on the staging classification. Z Krebsforsch 83:323
Novak S, Caravec J, Trowbridge AA, Peterson RF, White RR (1975) Primary lymphomas of the gastrointestinal tract. South Med J 72:1154–1158
Palmer ED (1950) The sarcomas of the stomach. Am J Dig Dis 17:86
Peters U, Schoppe WD, Berges FW (1987) deDiagnostik gastrointestinaler Non-Hodgkin-Lymphome. Dtsch Med Wochenschr 112:510–513
Rosen CB, van Heerden JA, Martin JK, Wold LE, Ilstrup DM (1987) Is an aggressive surgical approach to the patient with gastric lymphoma warranted? Ann Surg 205:634–640
Rosen HR, Heinz R, Marcell AP, Hanak H (1988) Lymphome des Gastrointestinaltraktes. Chirurg 59:244–247
Ruf G, Salm R, Koch HK (1983) Malignes Lymphom im Magen. Chir Praxis 32:627–636
Sheridan WP, Medley G, Brodie GN (1985) Non-Hodgkin's lymphoma of the stomach: a prospective pilot study of surgery plus chemotherapy in early and advanced disease. J Clin Oncol 3:495–500
Shin MH, Karas M, Nisce L, Lee BJ, Filippa A (1982) Management of primary gastric lymphoma. Ann Surg 195:196–202
Siegert W, Hackl G, Löhrs U, Hohn D (1983) Maligne Non-Hodgkin-Lymphome mit gastrointestinaler Erstmanifestation. Onkologie 6:235
Steinke B, Enöhr HC, Gärtner HU, Waller HD (1981) Non-Hodgkin- Lymphome mit gastrointestinaler Manifestation. Onkologie 4:193–200
Strohmeyer T, Ruf G, Salm R, Schöffel U, Lausen M (1988) Diagnostik und chirurgische Therapie primärer und sekundärer Lymphome des Magens. Med Klin 83:429–433
Wernicke J, van Gaisberg U (1984) Endoskopische Aspekte maligner Non-Hodgkin-Lymphome des Magens. Z Gastroenterol 22:563–572
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Herrn Professor Dr. H. Lüdeke zum 80. Geburtstag
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David, A., Schlossert, D., Möckel, W. et al. Primäre Non-Hodgkin-Lymphome des magens. Langenbecks Arch Chiv 374, 334–339 (1989). https://doi.org/10.1007/BF01262812
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DOI: https://doi.org/10.1007/BF01262812