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Electron optical studies of bovine viral diarrhea-mucosal disease virus (BVDV)

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Summary

After concentration and purification steps involving ultracentrifugation, density gradient centrifugation in potassium tartrate and rate zonal centrifugation in saccharose the virus of bovine virus diarrhea-mucosal disease of cattle (strain Oregon C24 V) was studied electron microscopically. The virion consists of an envelope without projections and a nucleocapsid probably displaying a cubical symmetry. The particle has a diameter of 57±7 mμ the core accounting for 24±4 mμ.

The morphological relationship to other viruses is discussed.

Zusammenfassung

Nach der Konzentration durch Ultrazentrifugierung und nach Reinigungsschritten durch Dichtezentrifugierung in Kaliumtartrat und Zonenzentrifugierung in Saccharose wurde das Virus der bovinen Virusdiarrhoe-Mucosal Disease (Stamm Oregon C24 V) elektronenoptisch dargestellt. Das Virion besteht aus einer Hülle ohne Projektionen und einem wahrscheinlich kubisch-symmetrischen Nukleokapsid. Der Durchmesser des Virion beträgt 57±7 mμ, der des Innenkörpers 24±4 mμ.

Die morphologische Verwandtschaft mit anderen Viren wird diskutiert.

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  1. J. Maess

    Present address: Bundesforschungsanstalt für Viruskrankheiten der Tiere, Tübingen am Neckar, BRD

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  1. Bundesforschungsanstalt für Viruskrankheiten der Tiere, Tübingen am Neckar, BRD

    Eva Reczko

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Maess, J., Reczko, E. Electron optical studies of bovine viral diarrhea-mucosal disease virus (BVDV). Archiv f Virusforschung 30, 39–46 (1970). https://doi.org/10.1007/BF01262581

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