Summary
The pathology of so-called Takayasu's disease is an allergic-hyperergic granulomatous arteriitis affecting predominantly the aortic arch and its major branches in young women. The arteriitis seems to begin in the adventitia, i.d. in the vasa vasorum, with extension to the media. The restoration of the carotid artery and surgical therapy of hypertension caused by atypical coarctation of theaorta or renovascular lesions are needed, for the occlusive process of the carotid artery causes not infrequently blindness and the patients die mostly of cardiac or cerebrovascular insufficiency due to hypertension.
Although the prosthetic bypass graft from the ascending aorta to the internal carotid artery is effective for the carotid-insufficiency, the problems of operative indication remain to be resolved.
Zusammenfassung
Bei der Takayasu-Arteriitis handelt es sich um eine allergischhyperergische granulomatöse Entzündung, die meistens den Aortenbogen und dessen große Äste bei jungen Frauen befällt. Die Arteriitis scheint in der Adventitia, nämlich in den Vasa vasorum, zu beginnen.
Da die ophthalmologische Komplikation sehr gravierend ist und die Patienten meistens an Herzversagen oder cerebralen Durchblutungsstörungen wegen einer Hypertonie sterben, ist die rechtzeitige Wiederherstellung der Carotiden und die Korrektur der Koarktation oder der renovasculären Hypertonie entscheidend.
Für die Carotisinsuftizienz ist der Aorta ascendens-A. carotis int.-By-pass zwar erfolgreich, aber die Beurteilung über die rekonstruktive Operation der Carotiden steht noch immer im Brennpunkt des Interesses.
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Shionoya, S., Ban, I., Nakata, Y. et al. Chirurgische Therapie und Pathologie der Takayasu-Arteriitis. Langenbecks Arch Chiv 333, 47–58 (1973). https://doi.org/10.1007/BF01261199
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DOI: https://doi.org/10.1007/BF01261199