Summary
In animal experiments it was examined, to what extent prophylactic application of Somatostatin is able to prevent the stress-induced ulcer of the rat.
32 male Wistar rats were exposed to a combined immobilisation-hypoxia-stress. Somatostatin was given intraperitoneally as bolus and intravenously as a continuous infusion. The results indicated that Somatostatin lowers significantly the incidence rate of stress-induced gastric ulcers in the rat.
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Mattes, P., Lauterbach, H.H. & Raptis, S. Prevention of stress ulcer by Somatostatin in rats. Langenbecks Arch Chiv 341, 297–301 (1976). https://doi.org/10.1007/BF01254584
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DOI: https://doi.org/10.1007/BF01254584