Summary
A simple method of dystopic cardiac transplantation as a left-heart bypass was experimentally studied and details of the method are described. The hemodynamic investigation of this biological assisted circulation on the normal and failing heart, which was induced by subtotal occlusion of the asc. aorta, as well as its longtime support of the chronically damaged left myocardium showed the efficacy of this method. The advantages of this biological method in comparison to that of mechanical devices and orthotopic cardiac transplantation are discussed.
Zusammenfassung
Eine relativ einfache Methode der dystopen Herztransplantation als Links-Herz-Bypass wird experimentell untersucht und die Methodik im einzelnen beschrieben. Akute hämodynamische Untersuchungen dieser biologisch assistierten Zirkulation des normalen und infolge subtotaler Okklusion der Aorta ascendens insuffizienten Herzens sowie Langzeitbeobachtungen dokumentieren die Effektivität dieser Methode. Die Vorteile dieser Methode gegenüber den mechanischen Systemen und der orthotopen Herztransplantation werden diskutiert.
Similar content being viewed by others
Literatur
Arealis, E. G.: A modification of the intrathoracic parallel heart transplant technique. J. surg. Res.12, 298–302 (1972)
Bing, R. J.: Cardiac metabolism. Physiol. Rev.45, 171–213 (1965)
Chaptal, P.-A., Akutsu, T., Kantrowitz, A., Brooklyn, N. Y.: Hemodynamic effects of a mechanical auxiliary ventricle following induced heart failur in dogs. J. thorac. cardio vasc. Surg. 52, 376–385 (1966)
Demikhov, V. P.: Experimental transplantation of vital organs. New York: Consultants Bureau 1962
Fleming, W. H., Aaby, G. V., Randolph, G.: A comparative study of arterio-arterial and intra-aortic balloon counterpulsation in the therapy of cardiogenic shock. J. thorac. cardiovasc. Surg.60, 818–828 (1970)
Galletti, P. M.: Discussion on venoarterial pumping with oxygenation in conference on mechanical devices to assist the failing heart. Washington, D.C.: National Academy of Sciences — National Research Council 1966
Hill, J. D., Bramson, M. L., Rapaport, E., Scheinman, M., Osborn, J. J., Gerbode, F.: Experimental and clinical experiences with prolonged oxygenation and assisted circulation. Ann. Surg.170, 448–459 (1969)
Kennedy, J. H.: Assisted circulation: An extended concept of cardiopulmonary resuscitation. J. thorac. cardiovasc. Surg.57, 688–701 (1969)
Marcial, M. B., Armelin, E., Stolf, N., Piantino, C., Macruz, R., Verginelli, G., Zerbini, G. J.: Assisted circulation with an auxiliary heart transplant. J. thorac. cardiovasc. Surg.63, 696–704 (1972)
Mc Gough, E. C., Brewer, P. L., Reemtsma, K.: The parallel heart: studies of intrathoracic auxiliary cardiac transplant. J. thorac. cardiovasc. Surg.63, 696–704 (1972)
Nasseri, M., Eisele, R., Kötter, D., Paeprer, H.: Dystope Herztransplantation als Hilfspumpe. IAG. Vortragsreihe Berlin-Transplant (1971)
Nasseri, M., Eisele, R., Kötter, D., Paeprer, H.: Biological left heart bypass. Abstract of Congress European Society for Exp. Surgery. Amsterdam, April (1972)
Nasseri, M., Schaldach, M., Bücherl, E. S.: Hämodynamik des suffizienten und insuffizienten Herzens bei einer intracorporalen Pumpe. Verb. dtsch. Ges. Kreisl.-Forsch. 222 (1967)
Small, M. L., Gerbode, F.: Evaluation of left heart bypass in standardized experimental situation of acute heart failure. J. thorac. cardiovasc. Surg.54, 777–784 (1967)
Suros, J., Woods, J. E.: A synchronized intrathoracic auxiliary heart transplant in parallel. J. thorac. cardiovasc. Surg.63, 415–424 (1973)
Author information
Authors and Affiliations
Additional information
Teilweise vorgetragen auf dem Kongreß Société international de chirurgie, Sept. 1973.
Mit Unterstützung der interdisziplinären Arbeitsgruppe Berlin-Transplant.
Rights and permissions
About this article
Cite this article
Nasseri, M., Eisele, R., Kötter, D. et al. Neue Wege der Kreislaufunterstützung. Langenbecks Arch Chiv 338, 225–233 (1975). https://doi.org/10.1007/BF01254355
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01254355