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Studies on primary atypical pneumonia virus

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Conclusion

  1. 1.

    The virus of primary atypical pneumonia can be isolated and fixed by the mouse-intracerebral as well as the chorioallantoic membrane inoculations.

  2. 2.

    Patient sera at initial febrile stage did not neutralize this fixed virus, but the neutralizing power increased following the passage of time.

  3. 3.

    All the three fixed strains proved immunoserologically as the same.

  4. 4.

    Complement fixation test for the convalescent serum with the fixed virus is suitable not only for identification of the virus, but also for clinical diagnosis.

  5. 5.

    Monkeys (Macaca fuscata) inoculated with this fixed virus showed a comparable X-ray photograph as in the human beings.

  6. 6.

    Size of the virus is estimated as 52–82 mμ by ultrafiltration and 100–200 mμ by electron microscopy.

These studies were aided by the Ministry of Welfare in 1951 and by the Ministry of Education in 1954.

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Authors and Affiliations

  1. Institute for Infectious Diseases, University of Tokyo, Japan

    Seiji Arakawa, Isamu Kondo & Tiaki Kaneko

  2. Laboratory of Smallpox and Other Viral Diseases, Japan

    Seiji Arakawa, Isamu Kondo & Tiaki Kaneko

  3. School of Medicine, Department of Bacteriology, Yokohama University, Japan

    Nobumasa Goto

Authors
  1. Seiji Arakawa
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  2. Isamu Kondo
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  3. Tiaki Kaneko
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  4. Nobumasa Goto
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Arakawa, S., Kondo, I., Kaneko, T. et al. Studies on primary atypical pneumonia virus. Archiv f Virusforschung 7, 88–109 (1956). https://doi.org/10.1007/BF01253895

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