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The inhibition of variola minor virus multiplication by rifampicin

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Summary

Rifampicin at concentrations of 100 μg/ml inhibits the growth of variola minor virus in HeLa cells. Synthesis of viral RNA, DNA, and early and late antigens occur in the presence of inhibitory concentrations of the drug, and its precise mode of action remains unclear.

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  1. T. H. Pennington

    Present address: Medical Research Council Virology Unit, Institute of Virology, Glasgow, Scotland

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    1. T. H. Pennington
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    Pennington, T.H. The inhibition of variola minor virus multiplication by rifampicin. Archiv f Virusforschung 31, 281–292 (1970). https://doi.org/10.1007/BF01253763

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    • DOI: https://doi.org/10.1007/BF01253763

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