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Mice with a slow response to lymphocytic choriomeningitis virus as a host of possible value for virus-induced immune disease studies

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Summary

The time of the clinical response of 5 week old mice to inoculation of LCM virus by the foot-pad route differed by about 36 hours between two albino strains and appeared to be genetically controlled. Following cerebral inoculation, the difference was about 18 hours. As reactions to this virus in mice are believed to be due to the host's immune response, these mice may be of value in further studies on this concept without resort to immunosuppression.

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References

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Author notes

  1. H. H. Skinner

    Present address: Animal Virus Research Institute, Pirbright, Surrey, England

Authors and Affiliations

  1. Animal Virus Research Institute, Pirbright, Surrey, England

    E. H. Knight

Authors
  1. H. H. Skinner
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  2. E. H. Knight
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Skinner, H.H., Knight, E.H. Mice with a slow response to lymphocytic choriomeningitis virus as a host of possible value for virus-induced immune disease studies. Archiv f Virusforschung 41, 185–190 (1973). https://doi.org/10.1007/BF01252764

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  • DOI: https://doi.org/10.1007/BF01252764

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