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Electron microscope observations of radiation-induced Hela giant cells

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Summary

An electron microscope study of X-ray produced giant Hela cells is described. The results extend earlier light microscope observations to the sub-microscopic region where clear differences from normal structures are apparent. Of particular interest are intra nuclear inclusions, nucleolar fragments, membrane abnormalities and possible mitochondrial changes.

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Author notes

  1. James K. Koehler Ph. D.

    Present address: Donner Laboratory and Donner Pavilion, University of California, Berkeley, USA

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    1. James K. Koehler Ph. D.
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    Additional information

    This investigation was supported in part by the U. S. Atomic Energy Commission and in part by a predoctoral fellowship CF 8984 from the National Cancer Institute, Public Health Service.

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    Koehler, J.K. Electron microscope observations of radiation-induced Hela giant cells. Protoplasma 54, 493–503 (1962). https://doi.org/10.1007/BF01252637

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    • DOI: https://doi.org/10.1007/BF01252637

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