Summary
Green monkey kidney cells infected with SV40 are capable of supporting the multiplication of ECHO7 virus, vaccinia virus and simian adenovirus SV15.
Apparently the cell damaged by SV40 loses its ability to support the reproduction of ECHO7 virus only at the late stages of the infectious process.
Formation of adeno SV40 hybrids following joint multiplication of SV40 and simian adenoviruses SV15, SV23, and SV32 during 10 passages could not be demonstrated.
No detectable amounts of interferon were found in green monkey kidney cells infected with SV40 virus (large-plaque and small-plaque strains).
Influenza A virus inhibits the reproduction and the cytopathogenic activity of SV40 in green monkey kidney cells. One of the factors responsible for interference in this system is probably an interferon-like inhibitor induced by influenza virus.
Similar content being viewed by others
References
Allison, A. C.: Interference with, and interferon production by, polyoma virus. Virology15, 47 (1961).
Altstein, A. D., andN. N. Dodonova: Interfering activity of oncogenic simian virus SV40 in tissue culture. Proc. L. A. Tarassevich Memorial Conference, Tarassevich State Control Institute for Medical Biological Preparations, Moscow (1964), p. 185 (in Russian).
Altstein, A. D., N. N. Dodonova, andN. N. Vassiljeva: Effect of incubation temperature on the cytopathic activity, plaque formation, and multiplication virus SV40. Acta virol.9, 144 (1965).
Altstein, A. D., N. N. Dodonova, andN. N. Vassiljeva: Small-plaque and large-plaque variants of papovavirus SV40. Nature (Lond.)209, 1048 (1966).
Altstein, A. D., O. F. Sarycheva, andN. N. Dodonova: Detection of defective (T-antigen inducing, but noninfectious) particles in preparations of SV40 virus. Virology33, 744 (1967).
Altstein, A. D., N. N. Dodonova, andN. N. Vassiljeva: Correlation between the dose of SV40 virus and the time of appearance of the cytopathic effect in tissue culture. Vop. Virus.13, 60 (1968) (in Russian).
Altstein, A. D., N. N. Dodonova, andN. N. Vassiljeva: Study of plaque-forming activity of papovavirus SV40. Vop. Virus.13, 170 (1968) (in Russian).
Bykovski, A.: Improved method of embedding in metacrylates for preparation of ultrathin sections. Vop. Virus.6, 500 (1961) (in Russian).
Deinhaedt, F., andG. Henle: Interference between polyoma and vesicular stomatitis viruses in tissue culture. J. Immunol.84, 608 (1960).
Dideeholm, H.: Production of interferon by monkey kidney cells infected with simian virus 40. Arch. ges. Virusforsch.14, 39 (1963).
Friedman, R. M., A. S. Rabson, andW. R. Kirkham: Variation in interferon production by polyoma virus strains of differing oncogenicity. Proc. Soc. exp. Biol. (N.Y.)112, 347 (1963).
Gavrilov, V. I., N. N. Dodonova, andL. N. Kuborina: Epizootiology of adenovirus infections in monkeys M. rhesus. Vop. Virus.7, 99 (1962) (in Russian).
Hatano, M., andCh. Yoshie: Interfering action of myxovirus on polyoma virus in primary mouse embryo cell cultures. Arch. ges. Virusforsch.20, 314 (1967).
Hsiung, Gr. D.: Triple infection of monkey kidney cells by SV5, SV40 and measles viruses. IX. International Microbiological Congress, Abstracts, Medicine, Moscow (1966), p. 495.
Hsiung, G. D., andW. H. Gaylord: The vacuolating virus of monkeys. I. Isolation, growth characteristics and inclusion body formation. J. exp. Med.114, 975 (1961).
Huebner, D. J., E. M. Chanock, B. A. Rubin, andM. J. Casey: Induction by adenovirus type 7 of tumors in hamsters having the antigenic characteristics of 8V40 virus. Proc. nat. Acad. Sci. (Wash.)52, 1333 (1964).
Kuborina, L. N., N. V. Yaeoslavskaya, andA. D. Altstein: The use of plaque method without agar overlay for assay of small pox vaccine. Proc. L. A. Tarassevich memorial conference, Tarassevich State Control Institute for Medical Biological Preparations. Moscow (1965), p. 137 (in Russian).
Mettenheim, A. E.: Interferenz von SV40 gegen Impfstoffviren. Arch. ges. Virusforsch.19, 47 (1966).
Nadtochey, G. A., and A. D.Altstein: Electron microscopic studies on mixed infection in tissue culture (vaccinia, SV40 and simian adenovirus). IX. International Microbiological Congress, Abstracts, Medicine, Moscow (1966), p. 473.
O'Connor, G. T., A. S. Rabson, I. K. Berezesky, andF. J. Paul: Mixed infection with simian virus 40 and adenovirus 12. J. nat. Cancer Inst.31, 903 (1963).
Oxman, M. N., andP. H. Black: Inhibition of SV40 T-antigen formation by interferon. Proc. nat. Acad. Sci. (Wash.)55, 1133 (1966).
Plummer, G.: Interfering properties of simian viruses. Brit. J. exp. Path.44, 58 (1963).
Rabson, A. S., G. T. O'Connor, F. Paul, andI. K. Berezesky: Virus: mixed infection with herpes simplex and simian virus 40. Science151, 1535 (1966).
Rapp, F., J. L. Melnick, J. S. Butel, andT. Kitahara: The incorporation of SV40 genetic material into adenovirus 7 as measured by intranuclear synthesis of SV40 tumor antigen. Proc. nat. Acad. Sci. (Wash.)52, 1348 (1964).
Reynolds, E. S.: The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. J. Cell Biol.17, 208 (1963).
Rowe, W. P., andS. Baum: Evidence for a possible hybrid between adenovirus type 7 and SV40 viruses. Proc. nat. Acad. Sci. (Wash.)52, 1340 (1964).
Todaro, G. J., andS. Baron: The role of interferon in the inhibition of SV40 transformation of mouse cell line 3T3. Proc. nat. Acad. Sci. (Wash.)54, 752 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Altstein, A.D., Dodonova, N.N., Nadtochey, G.A. et al. Interaction between SV40 and other viruses in tissue culture: Interference and double infection. Archiv f Virusforschung 28, 7–18 (1969). https://doi.org/10.1007/BF01250840
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01250840