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Effect of antimetabolites and actinomycin D on the replication of HADEN, a bovine parvovirus

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Summary

A hemadsorbing enteric virus (HADEN), isolated from the gastrointestinal tract of cattle and previously classified as a bovine enterovirus, was found to induce Feulgen-positive intranuclear inclusions and to be inhibited in its replication by FUDR, BUDR and actinomycin D, indicating DNA as genetic material. Because of this fact and the other known properties of HADEN virus it should be considered a bovine parvovirus.

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Author notes

  1. J. Storz

    Present address: Department of Microbiology, College of Veterinary Medicine and Biomedical Sciences Colorado State University, Fort Collins, Colorado, USA

Authors and Affiliations

  1. Department of Microbiology, College of Veterinary Medicine and Biomedical Sciences Colorado State University, Fort Collins, Colorado, USA

    G. S. Warren

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  1. J. Storz
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  2. G. S. Warren
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Storz, J., Warren, G.S. Effect of antimetabolites and actinomycin D on the replication of HADEN, a bovine parvovirus. Archiv f Virusforschung 30, 271–274 (1970). https://doi.org/10.1007/BF01250201

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  • DOI: https://doi.org/10.1007/BF01250201

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