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VERO cells (cercopithecus aethiops kidney) — growth characteristics and viral susceptibility for use in diagnostic virology

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Summary

An investigation of some of the characteristics of the VERO cell line (Cercopithecus aethiops kidney) is reported, in which the suitability of the cells for use in routine diagnostic virology was examined. VERO cells will:

  1. 1.

    grow to monolayers as rapidly as other heteroploid cell lines, but will maintain as usable monolayers in conventional maintenance medium for a significantly longer time;

  2. 2.

    grow a selection of ten representative viruses to a higher titre than will two other heteroploid lines or two cell strains;

  3. 3.

    support the growth of a very wide range of viruses with development in most instances of a characteristic cytopathic effect.

VERO cells are recommended as possible substitutes for primary monkey kidney cell cultures, and are superior in overall performance to primary human amnion, HEp-2 or HeLa cells for diagnostic use in virology.

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Author notes

  1. R. G. Sommerville

    Present address: Virology Section, University Department of Microbiology, Belvidere Hospital, Glasgow, Scotland

Authors and Affiliations

  1. Virology Section, University Department of Microbiology, Belvidere Hospital, Glasgow, Scotland

    D. E. Macfarlane

Authors
  1. D. E. Macfarlane
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  2. R. G. Sommerville
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Macfarlane, D.E., Sommerville, R.G. VERO cells (cercopithecus aethiops kidney) — growth characteristics and viral susceptibility for use in diagnostic virology. Archiv f Virusforschung 27, 379–385 (1969). https://doi.org/10.1007/BF01249659

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  • DOI: https://doi.org/10.1007/BF01249659

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