Summary
Three types of mixed populations of poliovirus type 1 (strain Brunhilde) and type 3 (strain Saukett) were prepared. These populations were separated on calcium phosphate columns and the adsorption patterns studied. The adsorption patterns of double-neutralizable particles represented the average of the adsorption patterns of the parental strains. Chromatography separated double-neutralizable particles of the three types of mixed populations were cultured. They produced a mixed population consisting of particles neutralized by serum against strain Brunhilde, of particles neutralized by serum against strain Saukett, and of doubleneutralized particles.
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Koza, J. Chromatographic analysis of mixed populations of poliovirus. Archiv f Virusforschung 27, 244–254 (1969). https://doi.org/10.1007/BF01249647
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DOI: https://doi.org/10.1007/BF01249647