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Silicate particles engulfed in human alveolar macrophages: An analytical electron microscopy study

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Abstract

The chemical composition and crystalline structure of silicate particles engulfed in human alveolar macrophages were investigated by transmission analytical electron microscopy. A crystalline ZrSiO4 and an amorphous Si2AlO4 particle were identified. Small crystalline Fe microparticles (2–4 nm), which are likely ferritin molecules, were found concentrated mainly at the amorphous particle-tissue interface.

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References

  1. J. BignonHealth Related Effects of Phyllosilicates, NATO ASI Series, Springer, Berlin Heidelberg New York Tokyo, 1990, p. 21.

    Google Scholar 

  2. J. E. Gallagher, G. George, A. R. Brody,Am. Rev. Respir. Dis. 1987,135, 1345.

    Google Scholar 

  3. R. P. Nolan, A. M. Langer, J. S. Harington, G. Oster, I. J. Selikoff,Environ. Res. 1981,26, 503.

    Google Scholar 

  4. G. Cliff, G. W. Lorimer,J. Microsc. 1975,103, 203.

    Google Scholar 

  5. A. D. Roming, J. I. Goldstein,Met. Trans. 1980,11A, 1151.

    Google Scholar 

  6. R. D. Heidenreich,Fundamentals of Transmission Electron Microscopy, Wiley, New York, 1964, p. 174.

    Google Scholar 

  7. R. F. Egerton,Electron Energy Loss Spectroscopy in the Electron Microscope, Plenum, New York, 1986.

    Google Scholar 

  8. R. F. Egerton,Ultramicroscopy 1979,4, 169.

    Google Scholar 

  9. C. Colliex,Advances in Optical and Electron Microscopy, Academic Press, London, 1984.

    Google Scholar 

  10. P. Scherrer,Göttinger Nachr. 1918,2, 98.

    Google Scholar 

  11. F. D. Pooley,Environ. Res. 1972,5, 369.

    Google Scholar 

  12. J. P. Berry, P. Henoc, P. Galle, R. Pariente,Am. J. Path. 1976,83, 427.

    Google Scholar 

  13. C. Janguillame, J. P. Berry, C. Colliex, P. Galle, M. Tence, P. Trebbia,J. Physique 1984,45, C2–577.

    Google Scholar 

  14. T. C. Iancu,Electron Microsc. Rev. 1992,5, 209.

    Google Scholar 

  15. E. R. Bauminger, T. C. Iancu, G. Link, A. Pinson, C. Hershko,Hyperfine Interactions 1987,33, 249.

    Google Scholar 

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Diociaiuti, M., Falchi, M. & Paoletti, L. Silicate particles engulfed in human alveolar macrophages: An analytical electron microscopy study. Mikrochim Acta 114, 285–291 (1994). https://doi.org/10.1007/BF01244554

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