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Reduced growth hormone response to apomorphine in schizophrenic patients with poor premorbid social functioning

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Summary

The apomorphine-induced growth hormone (GH) response of 16 drug-free schizophrenic patients and nine control subjects were studied. The sub-group of nine patients with poor premorbid psychosocial functioning had a significantly lower GH response than the controls. Additional evidence for state dependent effects is provided.

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Author information

Author notes

  1. D. P. van Kammen

    Present address: Psychiatry Service, VA Medical Center and Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

Authors and Affiliations

  1. Psychiatry Service, VA Medical Center, Seattle, Washington

    K. L. Malas

  2. Baltimore, Maryland, USA

    E. A. de Fraites (private practice)

  3. Department of Neuroscience, McMaster University, Hamilton, Ontario, Canada

    G. M. Brown

  4. Clinical Center, NIMH, Bethesda, Maryland, USA

    P. W. Gold

Authors
  1. K. L. Malas
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  2. D. P. van Kammen
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  3. E. A. de Fraites
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  4. G. M. Brown
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  5. P. W. Gold
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Malas, K.L., van Kammen, D.P., de Fraites, E.A. et al. Reduced growth hormone response to apomorphine in schizophrenic patients with poor premorbid social functioning. J. Neural Transmission 69, 319–324 (1987). https://doi.org/10.1007/BF01244352

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  • DOI: https://doi.org/10.1007/BF01244352

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