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FIA-Fluorimetric assembly for the determination of noradrenaline hydrochloride by a solid-phase reactor with immobilized hexacyanoferrate(III)

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Abstract

An FIA assembly provided with immobilized hexacyanoferrate(III) is proposed for the fluorimetric determination of noradrenaline hydrochloride. The oxidative reagent is immobilized by means of a strong anion-exchange resin. The FIA manifold is very simple and the calibration graph is linear over the range 0.5–75mgl−1 noradrenaline hydrochloride with an r.s.d of 0.88% (17 replicates) and a sample throughput of 84h−1. Foreign compounds such as NaCl, sucrose, lactose and sodium sulfate caused no significant errors. The procedure is applied to the determination of noradrenaline in a medicinal formulation.

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Author notes

  1. Gustavo A. Rivas

    Present address: Departamento de Fisico-Química, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Suc 16, CC 61, 5016, Córdoba, Argentina

Authors and Affiliations

  1. Departmento de Quimica Analitica, Universitat de Valencia, Valencia, Spain

    Salome Laredo Ortiz & Gustavo A. Rivas

  2. Departamento de Quimica, CEU, 46113, Moncada, Valencia, Spain

    José Martínez Calatayud

Authors
  1. Salome Laredo Ortiz
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  2. Gustavo A. Rivas
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  3. José Martínez Calatayud
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Ortiz, S.L., Rivas, G.A. & Calatayud, J.M. FIA-Fluorimetric assembly for the determination of noradrenaline hydrochloride by a solid-phase reactor with immobilized hexacyanoferrate(III). Mikrochim Acta 126, 69–72 (1997). https://doi.org/10.1007/BF01242663

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  • DOI: https://doi.org/10.1007/BF01242663

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