Summary
By temporary exposure of FMDV-infected calf kidney cultures to homologous antibodies a persistent infection was observed. The persistently infected cultures showed resistance to challenge with 100 TCD50 of the FMDV-strain used, for about 8–10 days after removal of antiserum, although persistent infection could be detected for additional 10 days. The persistent infection could be cured by antibody and in fully developed persistently infected cultures each 200th–600th cell was infected with cytopathogenic virus.
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Dinter, Z., Philipson, L. & Wesslén, T. Properties of foot-and-mouth disease virus in tissue culture. Archiv f Virusforschung 9, 582–593 (1960). https://doi.org/10.1007/BF01242145
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DOI: https://doi.org/10.1007/BF01242145