Skip to main content
SpringerLink
Log in

The nature of measles virus

  • Published:
Archiv für die gesamte Virusforschung Aims and scope Submit manuscript

Summary

Observations of the effect of halogen derivatives of deoxyuridine, known to affect the synthesis of deoxyviruses (DNA-containing viruses) show that measles virus replication is unaffected. This suggests that measles virus is a ribovirus (RNA-containing virus).

Measles virus causes haemagglutination of rhesus monkey red cells but possesses no neuraminidase, yet measles virus receptors on the red cell are destroyed by neuraminidase.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Cooper, P. D.: A chemical basis for the classification of animal viruses. Nature (Lond.)190, 302 (1961).

    Google Scholar 

  2. Toyoshima, K., S. Hata, M. Takahashi, T. Miki, andY. Okuno: Virological studies on measles virus. III. Morphological changes and virus growth in FL cultures. Biken's J.3, 241 (1960).

    Google Scholar 

  3. Atherton, J. G.: Unpublished observations (1960).

  4. Waterson, A. P.: Two kinds of myxovirus. Nature (Lond.)193, 1163 (1962).

    Google Scholar 

  5. Waterson, A. P., J. G. Cruickshank, G. Lawrence, andA. D. Kanarek: The nature of measles virus. Virology15, 379 (1961).

    Google Scholar 

  6. Plowright, W., J. G. Cruickshank, andA. P. Waterson: The morphology of rinderpest virus. Virology17, 118 (1962).

    Google Scholar 

  7. Cruickshank, J. G., A. P. Waterson, A. D. Kanarek, andD. M. Berry: The structure of canine distemper virus. Res. Vet. Sci.3, 485 (1962).

    Google Scholar 

  8. Schäfer, W., andR. Rott: Untereinheiten des Newcastle Disease und Mumpsvirus. Z. Naturforsch.14b, 629 (1959).

    Google Scholar 

  9. Waterson, A. P., andV. Hobson: Relationship between respiratory syncytial virus and Newcastle disease — parainfluenza group. Brit. med. J.2, 1166 (1962).

    Google Scholar 

  10. Rosen, L.: Hemagglutination and hemagglutination inhibition with measles virus. Virology13, 139 (1961).

    Google Scholar 

  11. Rosanoff, E. I.: Hemagglutination and Hemadsorption of Measles Virus. Proc. Soc. exp. Biol. (N.Y.)106, 563 (1961).

    Google Scholar 

  12. Herrmann, E. C., Jr.: Plaque inhibition test for detection of specific inhibitors of DNA containing viruses. Proc. Soc. exp. Biol. (N.Y.)107, 142 (1961).

    Google Scholar 

  13. Norrby, E. C. J.: Hemagglutination by Measles Virus. III. Identification of two different hemagglutinins. Virology19, 147 (1963).

    Google Scholar 

  14. Ada, G. L., E. L. French, andP. E. Lind: Purification and properties of neuraminidase fromVibrio cholerae. J. gen. Microbiol.24, 409 (1961).

    Google Scholar 

  15. Norrby, E. C. J.: Hemagglutination by measles virus. I. The production of haemagglutinin in tissue culture and the influence of different conditions on the haemagglutinating system. Arch. ges. Virusforsch.12, 153 (1962).

    Google Scholar 

  16. Norrby, E. C. J.: Hemagglutination by measles virus. II. Properties of the hemagglutinin and of receptors on the erythrocytes. Arch. ges. Virusforsch.12, 164 (1961).

    Google Scholar 

  17. Cohen, S.: Virus-induced acquisition of metabolic function. Fed. Proc.20, 641 (1961).

    Google Scholar 

  18. Tanami, Y., M. Pollard, andT. J. Starr: Replication pattern of psittacosis virus in a tissue culture system. Virology15, 22 (1961).

    Google Scholar 

  19. Smith, J. D., G. Freeman, M. Vogt, andR. Dulbecco: The nucleic acid of polyoma virus. Virology12, 185 (1960).

    Google Scholar 

  20. Salzman, N. P.: The rate of formation of vaccinia deoxyribonculeic acid and vaccinia virus. Virology10, 150 (1960).

    Google Scholar 

  21. Tamm, I.: Symposium on the experimental pharmacology and clinical use of antimetabolites. Part III. Metabolic antagonists and selective virus inhibition. Clin. Pharmacol. Ther.1, 777 (1960).

    Google Scholar 

  22. Weelock, E. F., andJ. Tamm; Biochemical basis for alteration in structure and function of HeLa cells infected with Newcastle disease virus. J. exp. Med.114, 617 (1961).

    Google Scholar 

  23. Simon, E. H.: Evidence for the nonparticipation of DNA in viral RNA synthesis. Virology13, 105 (1961).

    Google Scholar 

  24. Rich, M. A., A. G. Perez, andM. L. Eidinoff: Effect of 5-fluorodeoxyuridine on the proliferation of Rous sarcoma virus. Virology16, 98 (1962).

    Google Scholar 

  25. Heidelberger, C.: In “Biological Approaches to Cancer Chemotherapy” ed.R. J. C. Harris, p. 47, New York, Academic Press Inc. (1961).

    Google Scholar 

  26. Easterbrook, K. B., andC. I. Davern: The effect of 5-bromo-deoxyuridine on the multiplication of vaccinia virus. Virology19, 509 (1963).

    Google Scholar 

  27. Prusoff, W. H., V. S. Bakhle, andJ. F. McCrea: Incorporation of 5-iodo-2′-deoxyuridine into the deoxyribonucleic acid of vaccinia virus. Nature, (Lond.)199, 1310 (1963).

    Google Scholar 

  28. Lam, K. S. K., andJ. G. Atherton: Measles virus. Nature (Lond.)197, 820 (1963).

    Google Scholar 

  29. Sultanian, J. V., andI. Gordon: The nucleic acid of measles virus. Bact. Proc. p. 158 (1963).

  30. Levine, S., andW. Olson: Nucleic acids of measles and vesicular stomatitis virus. Proc. Soc. exp. Biol. (N. Y.)113, 630 (1963).

    Google Scholar 

  31. Goffe, A. P.: In discussion of papers on measles virus. Amer. J. Dis. Child.103, 325 (1962).

    Google Scholar 

  32. Horne, R. W., A. P. Waterson, P. Wildy, andA. E. Farnham: The structure and composition of the myxoviruses 1. Electron microscope studies of the structure of myxovirus particles by negative staining techniques. Virology11, 79 (1960).

    Google Scholar 

  33. Warren, J.: The relationships of the viruses of measles, canine distemper and rinderpest. Advanc. Virus. Res.7, 27 (1960).

    Google Scholar 

  34. Ruckle-Enders, G.: Comparative studies of monkey and human measlesvirus strains. Amer. J. Dis. Child.103, 297 (1962).

    Google Scholar 

Download references

Author information

Author notes

  1. K. S. K. Lam

    Present address: Microbiology Department, Australian National University, Canberra, Australia

Authors and Affiliations

  1. Department of Microbiology, University of Queensland, Brisbane, Australia

    J. G. Atherton & K. S. K. Lam

Authors
  1. J. G. Atherton
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. K. S. K. Lam
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

This work was supported by University of Queensland. Research Grant No. 438.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Atherton, J.G., Lam, K.S.K. The nature of measles virus. Archiv f Virusforschung 15, 413–421 (1965). https://doi.org/10.1007/BF01241768

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01241768

Keywords

Search

Navigation