Archiv für die gesamte Virusforschung

, Volume 34, Issue 2, pp 144–156 | Cite as

Salmonid viruses: Infectious pancreatic necrosis virus

Morphology, pathology, and serology of first european isolations
  • Ken Wolf
  • M. C. Quimby


Epizootics occurred among young trout in France, and the behavior and symptoms suggested infectious pancreatic necrosis (IPN) virus. Specimens preserved in glycerol were sent to the U.S.A. for virological examination. Virus was isolated from four of five lots, but neutralization with antiserum against ATCC VR299 strain IPN virus was incomplete. Electron microscopy, bioassay, histopathology, and serology were used to identify the viruses. The results showed the agents to be new strains of IPN virus with distinctive antigenicity and heretofore unknown lability at 4°C and marked vulnerability to a single freezing and thawing. A method of improving stability in storage was found. Electronmicrographs, tabular and graphic data are presented.


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Copyright information

© Springer-Verlag 1971

Authors and Affiliations

  • Ken Wolf
    • 1
  • M. C. Quimby
    • 1
  1. 1.U.S.D.I. Bureau of Sport Fisheries and WildlifeEastern Fish Disease LaboratoryKearneysvilleUSA

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